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Expression of concern

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Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Jia Wang, … , Maode Wang, Ichiro Nakano
Jia Wang, … , Maode Wang, Ichiro Nakano
Published September 1, 2020
Citation Information: J Clin Invest. 2020;130(9):5027-5027. https://doi.org/10.1172/JCI142404.
View: Text | PDF | Amended Article

Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2

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Abstract

Authors

Jia Wang, Peng Cheng, Marat S. Pavlyukov, Hai Yu, Zhuo Zhang, Sung-Hak Kim, Mutsuko Minata, Ahmed Mohyeldin, Wanfu Xie, Dongquan Chen, Violaine Goidts, Brendan Frett, Wenhao Hu, Hongyu Li, Yong Jae Shin, Yeri Lee, Do-Hyun Nam, Harley I. Kornblum, Maode Wang, Ichiro Nakano

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Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells
Motoshi Suzuki, … , Mamoru Kyogashima, Takashi Takahashi
Motoshi Suzuki, … , Mamoru Kyogashima, Takashi Takahashi
Published July 2, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI131245.
View: Text | PDF | Amended Article

Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

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Abstract

Authors

Motoshi Suzuki, Ke Cao, Seiichi Kato, Yuji Komizu, Naoki Mizutani, Kouji Tanaka, Chinatsu Arima, Mei Chee Tai, Kiyoshi Yanagisawa, Norie Togawa, Takahiro Shiraishi, Noriyasu Usami, Tetsuo Taniguchi, Takayuki Fukui, Kohei Yokoi, Keiko Wakahara, Yoshinori Hasegawa, Yukiko Mizutani, Yasuyuki Igarashi, Jin-ichi Inokuchi, Soichiro Iwaki, Satoshi Fujii, Akira Satou, Yoko Matsumoto, Ryuichi Ueoka, Keiko Tamiya-Koizumi, Takashi Murate, Mitsuhiro Nakamura, Mamoru Kyogashima, Takashi Takahashi

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Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
Meenakshi Hegde, … , Jordan S. Orange, Nabil Ahmed
Meenakshi Hegde, … , Jordan S. Orange, Nabil Ahmed
Published July 2, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI131246.
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Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

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Abstract

Authors

Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A. Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K.H. Chow, Vita S. Brawley, Tiara T. Byrd, Simone Krebs, Stephen Gottschalk, Winfried S. Wels, Matthew L. Baker, Gianpietro Dotti, Maksim Mamonkin, Malcolm K. Brenner, Jordan S. Orange, Nabil Ahmed

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HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers
Bilon Khambu, … , Zheng Dong, Xiao-Ming Yin
Bilon Khambu, … , Zheng Dong, Xiao-Ming Yin
Published May 1, 2019
Citation Information: J Clin Invest. 2019;129(5):2163-2163. https://doi.org/10.1172/JCI129233.
View: Text | PDF | Amended Article

HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers

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Abstract

Authors

Bilon Khambu, Nazmul Huda, Xiaoyun Chen, Daniel J. Antoine, Yong Li, Guoli Dai, Ulrike A. Köhler, Wei-Xing Zong, Satoshi Waguri, Sabine Werner, Tim D. Oury, Zheng Dong, Xiao-Ming Yin

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HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis
Celine Hernandez, … , Richard A. Friedman, Robert F. Schwabe
Celine Hernandez, … , Richard A. Friedman, Robert F. Schwabe
Published April 1, 2019
Citation Information: J Clin Invest. 2019;129(4):1803-1803. https://doi.org/10.1172/JCI128261.
View: Text | PDF | Amended Article

HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis

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Abstract

Authors

Celine Hernandez, Peter Huebener, Jean-Philippe Pradere, Daniel J. Antoine, Richard A. Friedman, Robert F. Schwabe

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The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis
Peter Huebener, … , Daniel J. Antoine, Robert F. Schwabe
Peter Huebener, … , Daniel J. Antoine, Robert F. Schwabe
Published March 4, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI126976.
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The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

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Authors

Peter Huebener, Jean-Philippe Pradere, Celine Hernandez, Geum-Youn Gwak, Jorge Matias Caviglia, Xueru Mu, John D. Loike, Rosalind E. Jenkins, Daniel J. Antoine, Robert F. Schwabe

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Brown adipose tissue–specific insulin receptor knockout shows diabetic phenotype without insulin resistance
Carmen Guerra, … , C. Ronald Kahn, Manuel Benito
Carmen Guerra, … , C. Ronald Kahn, Manuel Benito
Published January 2, 2019
Citation Information: J Clin Invest. 2019;129(1):437-437. https://doi.org/10.1172/JCI126191.
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Brown adipose tissue–specific insulin receptor knockout shows diabetic phenotype without insulin resistance

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Abstract

Authors

Carmen Guerra, Paloma Navarro, Angela M. Valverde, Monica Arribas, Jens Brüning, Leslie P. Kozak, C. Ronald Kahn, Manuel Benito

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ATP11B mediates platinum resistance in ovarian cancer
Myrthala Moreno-Smith, … , Gabriel Lopez-Berestein, Anil K. Sood
Myrthala Moreno-Smith, … , Gabriel Lopez-Berestein, Anil K. Sood
Published May 29, 2018
Citation Information: J Clin Invest. 2018. https://doi.org/10.1172/JCI122301.
View: Text | PDF | Amended Article

ATP11B mediates platinum resistance in ovarian cancer

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Abstract

Authors

Myrthala Moreno-Smith, J.B. Halder, Paul S. Meltzer, Tamas A. Gonda, Lingegowda S. Mangala, Rajesha Rupaimoole, Chunhua Lu, Archana S. Nagaraja, Kshipra M. Gharpure, Yu Kang, Cristian Rodriguez-Aguayo, Pablo E. Vivas-Mejia, Behrouz Zand, Rosemarie Schmandt, Hua Wang, Robert R. Langley, Nicholas B. Jennings, Cristina Ivan, Jeremy E. Coffin, Guillermo N. Armaiz, Justin Bottsford-Miller, Sang Bae Kim, Margaret S. Halleck, Mary J.C. Hendrix, William Bornman, Menashe Bar-Eli, Ju-Seog Lee, Zahid H. Siddik, Gabriel Lopez-Berestein, Anil K. Sood

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iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions
Jinhong Wu, … , Hongbo Chi, Xiao-Ping Zhong
Jinhong Wu, … , Hongbo Chi, Xiao-Ping Zhong
Published November 1, 2017
Citation Information: J Clin Invest. 2017;127(11):4216-4216. https://doi.org/10.1172/JCI98066.
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iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions

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Abstract

Authors

Jinhong Wu, Jialong Yang, Kai Yang, Hongxia Wang, Balachandra Gorentla, Jinwook Shin, Yurong Qiu, Loretta G. Que, W. Michael Foster, Zhenwei Xia, Hongbo Chi, Xiao-Ping Zhong

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Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation
Cong Jin, … , W. Michael Foster, Soman N. Abraham
Cong Jin, … , W. Michael Foster, Soman N. Abraham
Published September 18, 2017
Citation Information: J Clin Invest. 2017. https://doi.org/10.1172/JCI97321.
View: Text | PDF | Amended Article

Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation

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Abstract

Authors

Cong Jin, Christopher P. Shelburne, Guojie Li, Erin N. Potts, Kristina J. Riebe, Gregory D. Sempowski, W. Michael Foster, Soman N. Abraham

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