The Journal of Clinical Investigation is a premier venue for discoveries in basic and clinical biomedical science that will advance the practice of medicine.

The JCI was founded in 1924 and is published by the ASCI, a nonprofit honor organization of physician-scientists incorporated in 1908. See the JCI's Wikipedia entry for detailed information.

  • Impact Factor: 11.864 (2019). The JCI is one of the top journals in the “Medicine, Research & Experimental” Web of Science category.
  • Broad readership and scope. The JCI reaches readers across a wide range of medical disciplines and sectors. The journal publishes basic and phase I/II clinical research submissions in all biomedical specialties, including Autoimmunity, Gastroenterology, Immunology, Metabolism, Nephrology, Neuroscience, Oncology, Pulmonology, Vascular Biology, and many others.
  • Free access. All research is freely available to the public. The JCI deposits published research articles in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements.
  • Funding agency open access compliance. All research content is freely available to the public immediately upon publication. Authors with funding from agencies requiring Creative Commons Attribution licensing can be assured that the JCI will publish their paper using a CC BY 4.0 license to be fully compliant with funding mandates including those under Plan S. 
  • Preprint server and institutional repository posting. Authors are permitted to post manuscripts on bioRxiv and medRxiv, and are also permitted to post the final published version of the manuscript in institutional repositories. 

Submit your work

  • The journal considers research submissions in several categories.
  • Start your submission by accessing your JCI author account. If you don’t have an account yet, sign up here.
  • Click here for information on submission, manuscript and figure preparation, and editorial policies.
  • For any communication with us, reference the tracking number assigned by the journal noted in the acknowledgment of your submission. If you do not have this information, reference the manuscript title and corresponding author’s name. Send email to staff@the-jci.org or call 734-222-6050.
  • To avoid confusion regarding correspondence, inquiries, and decisions, the JCI will typically communicate only with corresponding authors of submissions.
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