In this episode, Kumar Sharma explains that urine adenine/creatinine is a marker for kidney failure in patients with diabetes, and endogenous adenine plays a potential causative role in diabetic kidney disease.
A committed champion of vaccines and vaccine diplomacy, Dr. Peter Hotez is the Dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology and Microbiology at the Baylor College of Medicine. As codirector of the Texas Children’s Hospital Center for Vaccine Development, Hotez has led the development and clinical trials of low-cost vaccines for hookworm infection, schistosomiasis, leishmaniasis, Chagas disease, and various coronaviruses. His persistence in the face of online and in-person harassment is impressive. This is an interview with Dr. Hotez from a stop on his book tour at Memorial Sloan Kettering Cancer Center on September 20, 2023.
In this episode, Sarah Blutt explains how this work demonstrates the power of organoids to understand and develop new therapies for diseases.
In this episode, Bikash Pattnaik and colleagues explain that their study encompasses the application of genomic medicine to treat monogenic retinal degeneration using base editing gene therapy delivered through novel nonviral platform.
In this episode, Ushma Neill interviews Elizabeth Jaffee, the Johns Hopkins–based oncologist and immunologist who led the clinical development of a first-gen cancer vaccine for pancreatic cancer and continues to use innovative approaches to identify the complex signaling pathways in tumor cells, the microenvironment, and the immune system toward the generation of cancer immunotherapies. All the while she's been a leader at the local, national, and international level, and currently is the chair of President Biden's Cancer Panel.