Targeting hepatic kisspeptin receptors and nonalcoholic fatty liver disease

In this episode, Stephania Guzman explains that this study establishes the kisspeptin receptor as a therapeutic target to treat nonalcoholic fatty liver disease.

Food addiction vulnerability in mice and humans and miRNA signatures

In this episode, Rafael Maldonado and Elena Martín-García explain how similar patterns of miRNAs signatures of food addiction vulnerability are present in animals and humans.

Efferocytosis induces VEGFC to improve cardiac injury and inflammation

In this episode, Guillermo Oliver and Ed Thorp discuss how cardiac VEGF-C is sourced from macrophages after efferocytosis to ameliorate cardiac injury and inflammation.

Gut-derived bacterial toxins and HIV-1 infection

In this episode, Souheil-Antoine Younes explains that their findings propose that toxic solutes from the gut bacterial flora may impair CD4+ T cell recovery during ART and may contribute to CD4+ T cell lymphopenia characteristic of INRs.

JCI’s Conversations with Giants in Medicine: Nora Volkow

In this episode, Ushma Neill interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA), about her work with trailblazing imaging studies of the brain’s frontal cortex and its dopamine-driven circuitry. Volkow has helped to reveal the neurobiological underpinnings of addiction and how drug-induced changes in brain chemistry contribute to its trademark craving, compulsion, and loss of control. Watch to hear more of Volkow’s views on the value of being an effective communicator and lessons learned from the double pandemic of opioids and COVID-19.