Viewpoint
Abstract
Available evidence suggests significant heterogeneity in the human immune response to SARS-CoV-2. In this Viewpoint, we examine the spectrum of SARS-CoV-2-associated clinical inflammatory syndromes identified in adult and pediatric populations to date. A better understanding of the immunopathologies and related clinical manifestations of these syndromes is necessary to improve their diagnosis and management.
Authors
Jill E. Weatherhead, Eva H. Clark, Tiphanie P. Vogel, Robert L. Atmar, Prathit A. Kulkarni
Abstract
Dr. Nancy Brown, Dean of the Yale School of Medicine, shares her perspective on the challenges facing women and minority faculty members and trainees in academic medicine and provides a reflection on how leaders in academic medicine can promote diversity, equity, and inclusion to enhance their success.
Authors
Nancy J. Brown
Abstract
Dr. John Carethers discusses challenges to the advancement of underrepresented minorities in medicine and effective strategies for institutions to promote diversity. He proposes that diversity should be a fourth pillar in the mission of academic medicine, alongside research, education, and clinical care.
Authors
John M. Carethers
Abstract
Dr. Rotonya Carr provides her thoughts on being one of the only Black women in her field, the persistent race-gender gap among academic medical center faculty, and possible solutions to retaining and promoting Black women in academia.
Authors
Rotonya M. Carr
Abstract
In the quest to provide treatment for COVID-19 patients, available therapies that have been approved for other indications but have insufficient evidence of safety and efficacy for use against COVID-19 have been considered. One of the unintended consequences of this approach is the potential creation of shortages, depriving existing patients who are benefiting from products based on their proven indications. Here, a pharmaceutical company outlines their ethical decision-making framework to guide decision-making and ensure equity of access to products.
Authors
Arthur L. Caplan, Joanne Waldstreicher, Karla Childers, Aran Maree
Abstract
Several important features of Multisystem Inflammatory Syndrome in Children (MIS-C) differentiate it from Kawasaki disease. Rowley et al. discuss what is known about MIS-C and the need to elucidate the specific immune mechanisms underlying hyperinflammatory syndromes caused by SARS-CoV-2 to advance potential targeted treatments and prevention efforts.
Authors
Anne H. Rowley, Stanford T. Shulman, Moshe Arditi
Abstract
Authors
Lorraine B. Ware, Kathleen L. Collins, John B. Hawley, Rexford S. Ahima
Abstract
This Viewpoint describes how physicians and researchers can utilize approaches based on relationship-centered care and structural competence to reduce racism and enhance trustworthiness in health care and biomedical research.
Authors
Lisa A. Cooper, Deidra C. Crews
Abstract
Authors
J. Wesley Pike, Mark B. Meyer
Abstract
Addressing racism from within health care is critically important to creating an equitable society. Here, we provide an actionable framework that can be implemented to build a culture of antiracism in health care systems.
Authors
Eugenia C. South, Paris D. Butler, Raina M. Merchant
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Copyright © 2020 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)