Author's Take
In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Kumar Sharma explains that urine adenine/creatinine is a marker for kidney failure in patients with diabetes, and endogenous adenine plays a potential causative role in diabetic kidney disease.
In this episode, Sarah Blutt explains how this work demonstrates the power of organoids to understand and develop new therapies for diseases.
In this episode, Bikash Pattnaik and colleagues explain that their study encompasses the application of genomic medicine to treat monogenic retinal degeneration using base editing gene therapy delivered through novel nonviral platform.
In this episode, Lasse Giil explains that activation of the kynurenine pathway in delirium leads to high brain concentrations the endogenous neurotoxin quinolinic acid.
In this episode, Nima Sharifi and Xiuxiu Li discuss how the BMX kinase regulates androgen and estrogen biosynthesis and is a drug target for sex steroid dependent cancers.
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ISSN: 0021-9738 (print), 1558-8238 (online)