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Author's Take

In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.

Targeting hepatic kisspeptin receptors and nonalcoholic fatty liver disease

In this episode, Stephania Guzman explains that this study establishes the kisspeptin receptor as a therapeutic target to treat nonalcoholic fatty liver disease.


Food addiction vulnerability in mice and humans and miRNA signatures

In this episode, Rafael Maldonado and Elena Martín-García explain how similar patterns of miRNAs signatures of food addiction vulnerability are present in animals and humans.


Efferocytosis induces VEGFC to improve cardiac injury and inflammation

In this episode, Guillermo Oliver and Ed Thorp discuss how cardiac VEGF-C is sourced from macrophages after efferocytosis to ameliorate cardiac injury and inflammation.


Gut-derived bacterial toxins and HIV-1 infection

In this episode, Souheil-Antoine Younes explains that their findings propose that toxic solutes from the gut bacterial flora may impair CD4+ T cell recovery during ART and may contribute to CD4+ T cell lymphopenia characteristic of INRs.


Tertiary lymphoid tissue expansion and kidney injury are promoted by CD153/CD30 signaling

In this episode, Motoko Yanagita and Yuki Sato explain that CD153-CD30 signaling is required for tertiary lymphoid tissue expansion and represents a therapeutic target for kidney diseases in the elderly.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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