Videos
The American Society for Clinical Investigation (ASCI) honors W. Kimryn Rathmell, MD, PhD, with the 2025 ASCI/Stanley J. Korsmeyer Award. Dr. Rathmell is recognized for her contributions to understanding the biologies driving cancer arising in the kidney and her advocacy for the careers of physician-scientists. Dr. Rathmell recently became CEO of The Ohio State University (OSU) Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. She is former director of the National Cancer Institute (NCI), before which she was Hugh Jackson Morgan Professor in the Department of Medicine at Vanderbilt University Medical Center and served on the faculty of the University of North Carolina at Chapel Hill. Dr. Rathmell was elected to the National Academy of Medicine and the American Academy of Arts and Sciences, is a fellow of the American Association for the Advancement of Science, and is a past president of the ASCI (2019–2020). Dr. Benjamin D. Humphreys, MD, PhD, ASCI Past President (2023–2024), Joseph Friedman Professor of Renal Diseases in Medicine, and Chief of the Division of Nephrology at Washington University in St. Louis, interviewed Dr. Rathmell at the AAP/ASCI/APSA Joint Meeting in Chicago in April 2025.
The American Society for Clinical Investigation (ASCI) honors Ann Chahroudi, MD, PhD, with the 2025 ASCI/Marian W. Ropes, MD, Award. Dr. Chahroudi is recognized for her contributions to the development of novel pediatric models of postnatal HIV and Zika virus infections. She is Professor and Vice Chair for Basic Science and Career Development in the Department of Pediatrics at Emory University School of Medicine. Dr. Chahroudi is also Founding Director of the Pediatric Residency Investigative Scholars at Emory program, Codirector of the Emory Center for AIDS Research, and co–principal investigator for the Martin Delaney Pediatric Adolescent Virus Elimination (PAVE) Collaboratory. Dr. Chahroudi was elected to the ASCI in 2022. Dr. Julie Saba, MD, PhD, an ASCI Physician-Scientist Engagement Committee member and The John & Edna Beck Chair in Pediatric Cancer Research at the University of California, San Francisco, interviewed Dr. Chahroudi in July 2025.
In this video, Dr. Seth J. Zost presents an antibody lineage from a single donor that binds the active site of influenza neuraminidase, cross-reacts with antigenically diverse viruses, and protects mice from infection.
In this episode, Marie Jeansson explains how the paper's findings suggest that TIE2 activation via angiopoietin-2 (ANGPT2)-binding and TIE2-activating antibody warrants investigation as a therapy in human CKD, where there is a substantial unmet medical need.
In this episode, Yi Bao explains the that the manuscript's findings establish STING activation as the key driver of T cell infiltration and the immune-hot tumor microenvironment in CDK12 mutant cancers, suggesting that dual CDK12/13 inhibitors and degraders activate anti-tumor immunity and potentiate responses to immunotherapies.
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