Viewpoint
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William Becker, W. Kimryn Rathmell
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Rares Drula, George A. Calin
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Kelsey R. van Straalen, Vincent Piguet, Johann E. Gudjonsson
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Amy B. Heimberger
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Hossein Ardehali
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Liping Zhao, Guojun Wu, Naisi Zhao
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Xiaochao Tan, Guan-Yu Xiao, Priyam Banerjee, Shike Wang, Jonathan M. Kurie
Abstract
Next-generation sequencing (NGS) applications for the diagnostics of infectious diseases has demonstrated great potential with three distinct approaches: whole-genome sequencing (WGS), targeted NGS (tNGS), and metagenomic NGS (mNGS, also known as clinical metagenomics). These approaches provide several advantages over traditional microbiologic methods, though challenges still exist.
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Kyle G. Rodino, Patricia J. Simner
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Karthik Vasan, Navdeep S. Chandel
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