JCI - Isn’t it ironic? Functional iron deficiency at the core of Parkinson’s disease pathobiology

Isn’t it ironic? Functional iron deficiency at the core of Parkinson’s disease pathobiology

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Figure 1

Iron accumulation in the substantia nigra is visible by MRI techniques in patients with PD.

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This iron may be in a trapped form, making it unavailable for the iron-dependent biological processes that are critical in dopaminergic cells, including mitochondrial respiration and dopamine synthesis.

Isn’t it ironic? Functional iron deficiency at the core of Parkinson’s disease pathobiology

Isn’t it ironic? Functional iron deficiency at the core of Parkinson’s disease pathobiology

Abstract

Authors

Figure 1

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