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Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin
Akulapalli Sudhakar, … , Dominic Cosgrove, Raghu Kalluri
Akulapalli Sudhakar, … , Dominic Cosgrove, Raghu Kalluri
Published January 2, 2020
Citation Information: J Clin Invest. 2020;130(1):552-552. https://doi.org/10.1172/JCI135305.
View: Text | PDF | Amended Article

Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin

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Abstract

Authors

Akulapalli Sudhakar, Pia Nyberg, Venkateshwar G. Keshamouni, Arjuna P. Mannam, Jian Li, Hikaru Sugimoto, Dominic Cosgrove, Raghu Kalluri

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Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells
Motoshi Suzuki, … , Mamoru Kyogashima, Takashi Takahashi
Motoshi Suzuki, … , Mamoru Kyogashima, Takashi Takahashi
Published November 1, 2019
Citation Information: J Clin Invest. 2019;129(11):5050-5050. https://doi.org/10.1172/JCI133806.
View: Text | PDF | Amended Article

Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells

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Abstract

Authors

Motoshi Suzuki, Ke Cao, Seiichi Kato, Yuji Komizu, Naoki Mizutani, Kouji Tanaka, Chinatsu Arima, Mei Chee Tai, Kiyoshi Yanagisawa, Norie Togawa, Takahiro Shiraishi, Noriyasu Usami, Tetsuo Taniguchi, Takayuki Fukui, Kohei Yokoi, Keiko Wakahara, Yoshinori Hasegawa, Yukiko Mizutani, Yasuyuki Igarashi, Jin-ichi Inokuchi, Soichiro Iwaki, Satoshi Fujii, Akira Satou, Yoko Matsumoto, Ryuichi Ueoka, Keiko Tamiya-Koizumi, Takashi Murate, Mitsuhiro Nakamura, Mamoru Kyogashima, Takashi Takahashi

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Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
Holbrook E. Kohrt, … , Lieping Chen, Ronald Levy
Holbrook E. Kohrt, … , Lieping Chen, Ronald Levy
Published June 3, 2019
Citation Information: J Clin Invest. 2019;129(6):2595-2595. https://doi.org/10.1172/JCI129688.
View: Text | PDF | Amended Article

Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer

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Abstract

Authors

Holbrook E. Kohrt, Roch Houot, Kipp Weiskopf, Matthew J. Goldstein, Ferenc Scheeren, Debra Czerwinski, A. Dimitrios Colevas, Wen-Kai Weng, Michael F. Clarke, Robert W. Carlson, Frank E. Stockdale, Joseph A. Mollick, Lieping Chen, Ronald Levy

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Targeting CD137 enhances the efficacy of cetuximab
Holbrook E. Kohrt, … , John Sunwoo, Ronald Levy
Holbrook E. Kohrt, … , John Sunwoo, Ronald Levy
Published June 3, 2019
Citation Information: J Clin Invest. 2019;129(6):2595-2595. https://doi.org/10.1172/JCI129689.
View: Text | PDF | Amended Article

Targeting CD137 enhances the efficacy of cetuximab

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Abstract

Authors

Holbrook E. Kohrt, A. Dimitrios Colevas, Roch Houot, Kipp Weiskopf, Matthew J. Goldstein, Peder Lund, Antonia Mueller, Idit Sagiv-Barfi, Aurelien Marabelle, Ruth Lira, Emily Troutner, Lori Richards, Amanda Rajapaska, Jonathan Hebb, Cariad Chester, Erin Waller, Anton Ostashko, Wen-Kai Weng, Lieping Chen, Debra Czerwinski, Yang-Xin Fu, John Sunwoo, Ronald Levy

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Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy
Lauren Elizabeth Walker, … , Annamaria Vezzani, Munir Pirmohamed
Lauren Elizabeth Walker, … , Annamaria Vezzani, Munir Pirmohamed
Published April 8, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI129285.
View: Text | PDF | Amended Article

Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy

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Abstract

Authors

Lauren Elizabeth Walker, Federica Frigerio, Teresa Ravizza, Emanuele Ricci, Karen Tse, Rosalind E. Jenkins, Graeme John Sills, Andrea Jorgensen, Luca Porcu, Thimmasettappa Thippeswamy, Tiina Alapirtti, Jukka Peltola, Martin J. Brodie, Brian Kevin Park, Anthony Guy Marson, Daniel James Antoine, Annamaria Vezzani, Munir Pirmohamed

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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers
Terence K. Lee, … , Ronnie T. Poon, Y. Peng Loh
Terence K. Lee, … , Ronnie T. Poon, Y. Peng Loh
Published March 18, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI128836.
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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

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Authors

Terence K. Lee, Saravana R.K. Murthy, Niamh X. Cawley, Savita Dhanvantari, Stephen M. Hewitt, Hong Lou, Tracy Lau, Stephanie Ma, Thanh Huynh, Robert A. Wesley, Irene O. Ng, Karel Pacak, Ronnie T. Poon, Y. Peng Loh

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Regenerating new heart with stem cells
Piero Anversa, … , Marcello Rota, Annarosa Leri
Piero Anversa, … , Marcello Rota, Annarosa Leri
Published December 3, 2018
Citation Information: J Clin Invest. 2018;128(12):5676-5676. https://doi.org/10.1172/JCI126075.
View: Text | PDF | Amended Article

Regenerating new heart with stem cells

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Abstract

Authors

Piero Anversa, Jan Kajstura, Marcello Rota, Annarosa Leri

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Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling
Alexandra Zanin-Zhorov, … , Ofer Lider, Irun R. Cohen
Alexandra Zanin-Zhorov, … , Ofer Lider, Irun R. Cohen
Published May 7, 2018
Citation Information: J Clin Invest. 2018. https://doi.org/10.1172/JCI121856.
View: Text | PDF | Amended Article

Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling

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Abstract

Authors

Alexandra Zanin-Zhorov, Liora Cahalon, Guy Tal, Raanan Margalit, Ofer Lider, Irun R. Cohen

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Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice
Almut Grenz, … , Michail Sitkovsky, Holger K. Eltzschig
Almut Grenz, … , Michail Sitkovsky, Holger K. Eltzschig
Published June 1, 2017
Citation Information: J Clin Invest. 2017;127(6):2438-2438. https://doi.org/10.1172/JCI94890.
View: Text | PDF | Amended Article

Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice

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Abstract

Authors

Almut Grenz, Jessica D. Bauerle, Julee H. Dalton, Douglas Ridyard, Alexander Badulak, Eunyoung Tak, Eóin N. McNamee, Eric Clambey, Radu Moldovan, German Reyes, Jost Klawitter, Kelly Ambler, Kristann Magee, Uwe Christians, Kelley S. Brodsky, Katya Ravid, Doo-Sup Choi, Jiaming Wen, Dmitriy Lukashev, Michael R. Blackburn, Hartmut Osswald, Imogen R. Coe, Bernd Nürnberg, Volker H. Haase, Yang Xia, Michail Sitkovsky, Holger K. Eltzschig

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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies
Sergio Gonzalez, … , Guy Lenaers, Nicolas Tricaud
Sergio Gonzalez, … , Guy Lenaers, Nicolas Tricaud
Published March 1, 2017
Citation Information: J Clin Invest. 2017;127(3):1115-1115. https://doi.org/10.1172/JCI92100.
View: Text | PDF | Amended Article

Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies

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Abstract

Authors

Sergio Gonzalez, Jade Berthelot, Jennifer Jiner, Claire Perrin-Tricaud, Ruani Fernando, Roman Chrast, Guy Lenaers, Nicolas Tricaud

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