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iPSC-derived β cells model diabetes due to glucokinase deficiency
Haiqing Hua, … , Rudolph L. Leibel, Dieter Egli
Haiqing Hua, … , Rudolph L. Leibel, Dieter Egli
Published January 17, 2017
Citation Information: J Clin Invest. 2017. https://doi.org/10.1172/JCI92775.
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iPSC-derived β cells model diabetes due to glucokinase deficiency

Abstract

Authors

Haiqing Hua, Linshan Shang, Hector Martinez, Matthew Freeby, Mary Pat Gallagher, Thomas Ludwig, Liyong Deng, Ellen Greenberg, Charles LeDuc, Wendy K. Chung, Robin Goland, Rudolph L. Leibel, Dieter Egli

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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
Cullen M. Taniguchi, … , Kohjiro Ueki, C. Ronald Kahn
Cullen M. Taniguchi, … , Kohjiro Ueki, C. Ronald Kahn
Published November 1, 2016
Citation Information: J Clin Invest. 2016;126(11):4387-4387. https://doi.org/10.1172/JCI90689.
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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

Abstract

Authors

Cullen M. Taniguchi, Kohjiro Ueki, C. Ronald Kahn

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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
Sabina Signoretti, … , Massimo Loda, Michele Pagano
Sabina Signoretti, … , Massimo Loda, Michele Pagano
Published November 1, 2016
Citation Information: J Clin Invest. 2016;126(11):4387-4387. https://doi.org/10.1172/JCI90690.
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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Abstract

Authors

Sabina Signoretti, Lucia Di Marcotullio, Andrea Richardson, Sridhar Ramaswamy, Beth Isaac, Montserrat Rue, Franco Monti, Massimo Loda, Michele Pagano

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In utero supplementation with methyl donors enhances allergic airway disease in mice
John W. Hollingsworth, … , David M. Brass, David A. Schwartz
John W. Hollingsworth, … , David M. Brass, David A. Schwartz
Published May 2, 2016
Citation Information: J Clin Invest. 2016;126(5):2012-2012. https://doi.org/10.1172/JCI87742.
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In utero supplementation with methyl donors enhances allergic airway disease in mice

Abstract

Authors

John W. Hollingsworth, Shuichiro Maruoka, Kathy Boon, Stavros Garantziotis, Zhuowei Li, John Tomfohr, Nathaniel Bailey, Erin N. Potts, Gregory Whitehead, David M. Brass, David A. Schwartz

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The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells
Rosa Marina Melillo, … , Alfredo Fusco, Massimo Santoro
Rosa Marina Melillo, … , Alfredo Fusco, Massimo Santoro
Published April 1, 2016
Citation Information: J Clin Invest. 2016;126(4):1603-1603. https://doi.org/10.1172/JCI87345.
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The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

Abstract

Authors

Rosa Marina Melillo, Maria Domenica Castellone, Valentina Guarino, Valentina De Falco, Anna Maria Cirafici, Giuliana Salvatore, Fiorina Caiazzo, Fulvio Basolo, Riccardo Giannini, Mogens Kruhoffer, Torben Orntoft, Alfredo Fusco, Massimo Santoro

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Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis
Shereen Ezzat, … , Gillian E. Wu, Sylvia L. Asa
Shereen Ezzat, … , Gillian E. Wu, Sylvia L. Asa
Published August 3, 2015
Citation Information: J Clin Invest. 2015;125(8):3303-3303. https://doi.org/10.1172/JCI83399.
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Targeted expression of a human pituitary tumor–derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

Abstract

Authors

Shereen Ezzat, Lei Zheng, Xian-Feng Zhu, Gillian E. Wu, Sylvia L. Asa

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FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer
Stephanie K. Watkins, … , Hideo Yagita, Arthur A. Hurwitz
Stephanie K. Watkins, … , Hideo Yagita, Arthur A. Hurwitz
Published May 1, 2015
Citation Information: J Clin Invest. 2015;125(5):2179-2179. https://doi.org/10.1172/JCI81878.
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FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer

Abstract

Authors

Stephanie K. Watkins, Ziqiang Zhu, Elena Riboldi, Kim A. Shafer-Weaver, Katherine E.R. Stagliano, Martha M. Sklavos, Stefan Ambs, Hideo Yagita, Arthur A. Hurwitz

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Novel APC-like properties of human NK cells directly regulate T cell activation
Jacob Hanna, … , Jane H. Buckner, Ofer Mandelboim
Jacob Hanna, … , Jane H. Buckner, Ofer Mandelboim
Published April 1, 2015
Citation Information: J Clin Invest. 2015;125(4):1763-1763. https://doi.org/10.1172/JCI81527.
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Novel APC-like properties of human NK cells directly regulate T cell activation

Abstract

Authors

Jacob Hanna, Tsufit Gonen-Gross, Jonathan Fitchett, Tony Rowe, Mark Daniels, Tal I. Arnon, Roi Gazit, Aviva Joseph, Karoline W. Schjetne, Alexander Steinle, Angel Porgador, Dror Mevorach, Debra Goldman-Wohl, Simcha Yagel, Michael J. LaBarre, Jane H. Buckner, Ofer Mandelboim

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Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
Deepti Malhotra, … , Peter Barnes, Shyam Biswal
Deepti Malhotra, … , Peter Barnes, Shyam Biswal
Published December 1, 2014
Citation Information: J Clin Invest. 2014;124(12):5521-5521. https://doi.org/10.1172/JCI79606.
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Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients

Abstract

Authors

Deepti Malhotra, Rajesh K. Thimmulappa, Nicolas Mercado, Kazuhiro Ito, Ponvijay Kombairaju, Sarvesh Kumar, Jinfang Ma, David Feller-Kopman, Robert Wise, Peter Barnes, Shyam Biswal

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Loss of nuclear pro–IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma
Clara Curiel-Lewandrowski, … , David M. Center, William W. Cruikshank
Clara Curiel-Lewandrowski, … , David M. Center, William W. Cruikshank
Published November 3, 2014
Citation Information: J Clin Invest. 2014;124(11):5085-5085. https://doi.org/10.1172/JCI79199.
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Loss of nuclear pro–IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma

Abstract

Authors

Clara Curiel-Lewandrowski, Hisato Yamasaki, Chuan Ping Si, Xiaoyi Jin, Yujun Zhang, Jillian Richmond, Marina Tuzova, Kevin Wilson, Beth Sullivan, David Jones, Nataliya Ryzhenko, Frederick Little, Thomas S. Kupper, David M. Center, William W. Cruikshank

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