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Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma
Sabine Mueller, … , Michael D. Prados, Hideho Okada
Sabine Mueller, … , Michael D. Prados, Hideho Okada
Published June 15, 2022
Citation Information: J Clin Invest. 2022;132(12):e162283. https://doi.org/10.1172/JCI162283.
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Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma

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Authors

Sabine Mueller, Jared M. Taitt, Javier E. Villanueva-Meyer, Erin R. Bonner, Takahide Nejo, Rishi R. Lulla, Stewart Goldman, Anu Banerjee, Susan N. Chi, Nicholas S. Whipple, John R. Crawford, Karen Gauvain, Kellie J. Nazemi, Payal B. Watchmaker, Neil D. Almeida, Kaori Okada, Andres M. Salazar, Ryan D. Gilbert, Javad Nazarian, Annette M. Molinaro, Lisa H. Butterfield, Michael D. Prados, Hideho Okada

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Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function
Mathilda Bedin, … , Corinne Antignac, Matias Simons
Mathilda Bedin, … , Corinne Antignac, Matias Simons
Published June 1, 2022
Citation Information: J Clin Invest. 2022;132(11):e161852. https://doi.org/10.1172/JCI161852.
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Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function

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Abstract

Authors

Mathilda Bedin, Olivia Boyer, Aude Servais, Yong Li, Laure Villoing-Gaudé, Marie-Josephe Tête, Alexandra Cambier, Julien Hogan, Veronique Baudouin, Saoussen Krid, Albert Bensman, Florie Lammens, Ferielle Louillet, Bruno Ranchin, Cecile Vigneau, Iseline Bouteau, Corinne Isnard-Bagnis, Christoph J. Mache, Tobias Schäfer, Lars Pape, Markus Gödel, Tobias B. Huber, Marcus Benz, Günter Klaus, Matthias Hansen, Kay Latta, Olivier Gribouval, Vincent Morinière, Carole Tournant, Maik Grohmann, Elisa Kuhn, Timo Wagner, Christine Bole-Feysot, Fabienne Jabot-Hanin, Patrick Nitschké, Tarunveer S. Ahluwalia, Anna Köttgen, Christian Brix Folsted Andersen, Carsten Bergmann, Corinne Antignac, Matias Simons

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RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis
Susan Li, … , Lionel B. Ivashkiv, Baohong Zhao
Susan Li, … , Lionel B. Ivashkiv, Baohong Zhao
Published May 16, 2022
Citation Information: J Clin Invest. 2022;132(10):e161196. https://doi.org/10.1172/JCI161196.
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RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis

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Authors

Susan Li, Christine H. Miller, Eugenia Giannopoulou, Xiaoyu Hu, Lionel B. Ivashkiv, Baohong Zhao

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The Eph receptor A4 plays a role in demyelination and depression-related behavior
Yuan Li, … , Albert H.C. Wong, Fang Liu
Yuan Li, … , Albert H.C. Wong, Fang Liu
Published May 16, 2022
Citation Information: J Clin Invest. 2022;132(10):e161559. https://doi.org/10.1172/JCI161559.
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The Eph receptor A4 plays a role in demyelination and depression-related behavior

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Authors

Yuan Li, Ping Su, Yuxiang Chen, Jing Nie, Ti-Fei Yuan, Albert H.C. Wong, Fang Liu

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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension
Thomas Bertero, … , Katherine A. Cottrill, Stephen Y. Chan
Thomas Bertero, … , Katherine A. Cottrill, Stephen Y. Chan
Published May 16, 2022
Citation Information: J Clin Invest. 2022;132(10):e161077. https://doi.org/10.1172/JCI161077.
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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

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Authors

Thomas Bertero, Yu Lu, Sofia Annis, Andrew Hale, Balkrishen Bhat, Rajan Saggar, Rajeev Saggar, W. Dean Wallace, David J. Ross, Sara O. Vargas, Brian B. Graham, Rahul Kumar, Stephen M. Black, Sohrab Fratz, Jeffrey R. Fineman, James D. West, Kathleen J. Haley, Aaron B. Waxman, B. Nelson Chau, Katherine A. Cottrill, Stephen Y. Chan

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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
Lauren Herl Martens, … , Eric J. Huang, Robert V. Farese Jr
Lauren Herl Martens, … , Eric J. Huang, Robert V. Farese Jr
Published January 4, 2022
Citation Information: J Clin Invest. 2022;132(1):e157161. https://doi.org/10.1172/JCI157161.
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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

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Authors

Lauren Herl Martens, Jiasheng Zhang, Sami J. Barmada, Ping Zhou, Sherry Kamiya, Binggui Sun, Sang-Won Min, Li Gan, Steven Finkbeiner, Eric J. Huang, Robert V. Farese Jr

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Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
Hui-Hua Li, … , David J. Glass, Cam Patterson
Hui-Hua Li, … , David J. Glass, Cam Patterson
Published January 4, 2022
Citation Information: J Clin Invest. 2022;132(1):e157373. https://doi.org/10.1172/JCI157373.
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Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

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Authors

Hui-Hua Li, Monte S. Willis, Pamela Lockyer, Nathaniel Miller, Holly McDonough, David J. Glass, Cam Patterson

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Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive
Marton Keszei, … , Scott B. Snapper, Lisa S. Westerberg
Marton Keszei, … , Scott B. Snapper, Lisa S. Westerberg
Published December 1, 2021
Citation Information: J Clin Invest. 2021;131(23):e156513. https://doi.org/10.1172/JCI156513.
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Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive

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Authors

Marton Keszei, Julien Record, Joanna S. Kritikou, Hannah Wurzer, Chiara Geyer, Meike Thiemann, Paul Drescher, Hanna Brauner, Laura Köcher, Jaime James, Minghui He, Marisa A.P. Baptista, Carin I.M. Dahlberg, Amlan Biswas, Sonia Lain, David P. Lane, Wenxia Song, Katrin Pütsep, Peter Vandenberghe, Scott B. Snapper, Lisa S. Westerberg

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MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop
Lili Jiang, … , Jun Li, Mengfeng Li
Lili Jiang, … , Jun Li, Mengfeng Li
Published November 15, 2021
Citation Information: J Clin Invest. 2021;131(22):e155916. https://doi.org/10.1172/JCI155916.
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MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

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Authors

Lili Jiang, Chuyong Lin, Libing Song, Jueheng Wu, Baixue Chen, Zhe Ying, Lishan Fang, Xiao Yan, Mian He, Jun Li, Mengfeng Li

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mTOR-dependent translation amplifies microglia priming in aging mice
Lily Keane, … , Michael T. Heneka, Melania Capasso
Lily Keane, … , Michael T. Heneka, Melania Capasso
Published October 15, 2021
Citation Information: J Clin Invest. 2021;131(20):e155208. https://doi.org/10.1172/JCI155208.
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mTOR-dependent translation amplifies microglia priming in aging mice

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Abstract

Authors

Lily Keane, Ignazio Antignano, Sean-Patrick Riechers, Raphael Zollinger, Anaelle A. Dumas, Nina Offermann, Maria E. Bernis, Jenny Russ, Frederike Graelmann, Patrick Neil McCormick, Julia Esser, Dario Tejera, Ai Nagano, Jun Wang, Claude Chelala, Yvonne Biederbick, Annett Halle, Paolo Salomoni, Michael T. Heneka, Melania Capasso

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