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Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
Holbrook E. Kohrt, … , Lieping Chen, Ronald Levy
Holbrook E. Kohrt, … , Lieping Chen, Ronald Levy
Published June 3, 2019
Citation Information: J Clin Invest. 2019;129(6):2595-2595. https://doi.org/10.1172/JCI129688.
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Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer

Abstract

Authors

Holbrook E. Kohrt, Roch Houot, Kipp Weiskopf, Matthew J. Goldstein, Ferenc Scheeren, Debra Czerwinski, A. Dimitrios Colevas, Wen-Kai Weng, Michael F. Clarke, Robert W. Carlson, Frank E. Stockdale, Joseph A. Mollick, Lieping Chen, Ronald Levy

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Targeting CD137 enhances the efficacy of cetuximab
Holbrook E. Kohrt, … , John Sunwoo, Ronald Levy
Holbrook E. Kohrt, … , John Sunwoo, Ronald Levy
Published June 3, 2019
Citation Information: J Clin Invest. 2019;129(6):2595-2595. https://doi.org/10.1172/JCI129689.
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Targeting CD137 enhances the efficacy of cetuximab

Abstract

Authors

Holbrook E. Kohrt, A. Dimitrios Colevas, Roch Houot, Kipp Weiskopf, Matthew J. Goldstein, Peder Lund, Antonia Mueller, Idit Sagiv-Barfi, Aurelien Marabelle, Ruth Lira, Emily Troutner, Lori Richards, Amanda Rajapaska, Jonathan Hebb, Cariad Chester, Erin Waller, Anton Ostashko, Wen-Kai Weng, Lieping Chen, Debra Czerwinski, Yang-Xin Fu, John Sunwoo, Ronald Levy

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Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy
Lauren Elizabeth Walker, … , Annamaria Vezzani, Munir Pirmohamed
Lauren Elizabeth Walker, … , Annamaria Vezzani, Munir Pirmohamed
Published April 8, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI129285.
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Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy

Abstract

Authors

Lauren Elizabeth Walker, Federica Frigerio, Teresa Ravizza, Emanuele Ricci, Karen Tse, Rosalind E. Jenkins, Graeme John Sills, Andrea Jorgensen, Luca Porcu, Thimmasettappa Thippeswamy, Tiina Alapirtti, Jukka Peltola, Martin J. Brodie, Brian Kevin Park, Anthony Guy Marson, Daniel James Antoine, Annamaria Vezzani, Munir Pirmohamed

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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers
Terence K. Lee, … , Ronnie T. Poon, Y. Peng Loh
Terence K. Lee, … , Ronnie T. Poon, Y. Peng Loh
Published March 18, 2019
Citation Information: J Clin Invest. 2019. https://doi.org/10.1172/JCI128836.
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An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

Abstract

Authors

Terence K. Lee, Saravana R.K. Murthy, Niamh X. Cawley, Savita Dhanvantari, Stephen M. Hewitt, Hong Lou, Tracy Lau, Stephanie Ma, Thanh Huynh, Robert A. Wesley, Irene O. Ng, Karel Pacak, Ronnie T. Poon, Y. Peng Loh

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Regenerating new heart with stem cells
Piero Anversa, … , Marcello Rota, Annarosa Leri
Piero Anversa, … , Marcello Rota, Annarosa Leri
Published December 3, 2018
Citation Information: J Clin Invest. 2018;128(12):5676-5676. https://doi.org/10.1172/JCI126075.
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Regenerating new heart with stem cells

Abstract

Authors

Piero Anversa, Jan Kajstura, Marcello Rota, Annarosa Leri

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Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling
Alexandra Zanin-Zhorov, … , Ofer Lider, Irun R. Cohen
Alexandra Zanin-Zhorov, … , Ofer Lider, Irun R. Cohen
Published May 7, 2018
Citation Information: J Clin Invest. 2018. https://doi.org/10.1172/JCI121856.
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Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling

Abstract

Authors

Alexandra Zanin-Zhorov, Liora Cahalon, Guy Tal, Raanan Margalit, Ofer Lider, Irun R. Cohen

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Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice
Almut Grenz, … , Michail Sitkovsky, Holger K. Eltzschig
Almut Grenz, … , Michail Sitkovsky, Holger K. Eltzschig
Published June 1, 2017
Citation Information: J Clin Invest. 2017;127(6):2438-2438. https://doi.org/10.1172/JCI94890.
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Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice

Abstract

Authors

Almut Grenz, Jessica D. Bauerle, Julee H. Dalton, Douglas Ridyard, Alexander Badulak, Eunyoung Tak, Eóin N. McNamee, Eric Clambey, Radu Moldovan, German Reyes, Jost Klawitter, Kelly Ambler, Kristann Magee, Uwe Christians, Kelley S. Brodsky, Katya Ravid, Doo-Sup Choi, Jiaming Wen, Dmitriy Lukashev, Michael R. Blackburn, Hartmut Osswald, Imogen R. Coe, Bernd Nürnberg, Volker H. Haase, Yang Xia, Michail Sitkovsky, Holger K. Eltzschig

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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies
Sergio Gonzalez, … , Guy Lenaers, Nicolas Tricaud
Sergio Gonzalez, … , Guy Lenaers, Nicolas Tricaud
Published March 1, 2017
Citation Information: J Clin Invest. 2017;127(3):1115-1115. https://doi.org/10.1172/JCI92100.
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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies

Abstract

Authors

Sergio Gonzalez, Jade Berthelot, Jennifer Jiner, Claire Perrin-Tricaud, Ruani Fernando, Roman Chrast, Guy Lenaers, Nicolas Tricaud

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iPSC-derived β cells model diabetes due to glucokinase deficiency
Haiqing Hua, … , Rudolph L. Leibel, Dieter Egli
Haiqing Hua, … , Rudolph L. Leibel, Dieter Egli
Published January 17, 2017
Citation Information: J Clin Invest. 2017. https://doi.org/10.1172/JCI92775.
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iPSC-derived β cells model diabetes due to glucokinase deficiency

Abstract

Authors

Haiqing Hua, Linshan Shang, Hector Martinez, Matthew Freeby, Mary Pat Gallagher, Thomas Ludwig, Liyong Deng, Ellen Greenberg, Charles LeDuc, Wendy K. Chung, Robin Goland, Rudolph L. Leibel, Dieter Egli

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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
Cullen M. Taniguchi, … , Kohjiro Ueki, C. Ronald Kahn
Cullen M. Taniguchi, … , Kohjiro Ueki, C. Ronald Kahn
Published November 1, 2016
Citation Information: J Clin Invest. 2016;126(11):4387-4387. https://doi.org/10.1172/JCI90689.
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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

Abstract

Authors

Cullen M. Taniguchi, Kohjiro Ueki, C. Ronald Kahn

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