Metabolism

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
Tadahiro Kitamura, … , Karen C. Arden, Domenico Accili
Tadahiro Kitamura, … , Karen C. Arden, Domenico Accili
Published December 15, 2002
Citation Information: J Clin Invest. 2002;110(12):1839-1847. https://doi.org/10.1172/JCI16857.
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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

Abstract

Research Article

Authors

Tadahiro Kitamura, Jun Nakae, Yukari Kitamura, Yoshiaki Kido, William H. Biggs III, Christopher V.E. Wright, Morris F. White, Karen C. Arden, Domenico Accili

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Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle
Blake B. Rasmussen, … , Douglas Paddon-Jones, Robert R. Wolfe
Blake B. Rasmussen, … , Douglas Paddon-Jones, Robert R. Wolfe
Published December 1, 2002
Citation Information: J Clin Invest. 2002;110(11):1687-1693. https://doi.org/10.1172/JCI15715.
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Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle

Abstract

Research Article

Authors

Blake B. Rasmussen, Ulf C. Holmbäck, Elena Volpi, Beatrice Morio-Liondore, Douglas Paddon-Jones, Robert R. Wolfe

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Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
Kazuaki Miyake, … , Hiroshi Sakaue, Masato Kasuga
Kazuaki Miyake, … , Hiroshi Sakaue, Masato Kasuga
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1483-1491. https://doi.org/10.1172/JCI15880.
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Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver

Abstract

Research Article

Authors

Kazuaki Miyake, Wataru Ogawa, Michihiro Matsumoto, Takehiro Nakamura, Hiroshi Sakaue, Masato Kasuga

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Impaired glucose phosphorylation and transport in skeletal muscle cause insulin resistance in HIV-1–infected patients with lipodystrophy
Georg M.N. Behrens, … , Georg Brabant, Reinhold E. Schmidt
Georg M.N. Behrens, … , Georg Brabant, Reinhold E. Schmidt
Published November 1, 2002
Citation Information: J Clin Invest. 2002;110(9):1319-1327. https://doi.org/10.1172/JCI15626.
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Impaired glucose phosphorylation and transport in skeletal muscle cause insulin resistance in HIV-1–infected patients with lipodystrophy

Abstract

Research Article

Authors

Georg M.N. Behrens, Anne-Rose Boerner, Klaus Weber, Joerg van den Hoff, Johann Ockenga, Georg Brabant, Reinhold E. Schmidt

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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1093-1103. https://doi.org/10.1172/JCI15693.
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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

Abstract

Research Article

Authors

I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord, Julia M. Keogh, Elizabeth Lawrence, Chizo Agwu, Veronica Sanna, Susan A. Jebb, Francesco Perna, Silvia Fontana, Robert I. Lechler, Alex M. DePaoli, Stephen O’Rahilly

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1191-1200. https://doi.org/10.1172/JCI16309.
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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Abstract

Research Article

Authors

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, Erik G. Lund, Ulla Andersson, Gertrud Schuster, Ingemar Björkhem, David W. Russell, Gosta Eggertsen

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Using SORLA to sort out human obesity
Vanessa Schmidt and colleagues demonstrate that the intracellular sorting receptor SORLA is an important regulator of lipid metabolism…
Published June 20, 2016
Scientific Show StopperMetabolism
Intracellular calcium leak recasts β cell landscape
Gaetano Santulli and colleagues reveal that RyR2 calcium channels in pancreatic β cells mediate insulin release and glucose homeostasis…
Published April 6, 2015
Scientific Show StopperMetabolism
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