Effect of acute hypoxia and hypercapnic acidosis on the development of acetylstrophanthidin-induced arrhythmias
John F. Williams Jr., … , Daniel L. Boyd, John F. Border
John F. Williams Jr., … , Daniel L. Boyd, John F. Border
Published August 1, 1968
Citation Information: J Clin Invest. 1968;47(8):1885-1894. https://doi.org/10.1172/JCI105879.
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Research Article

Effect of acute hypoxia and hypercapnic acidosis on the development of acetylstrophanthidin-induced arrhythmias

Abstract

The effect of acutely induced hypoxia, hypercapnic acidosis, and the combination of the two on the amount of acetylstrophanthidin (AS) required to produce cardiac arrhythmias was determined in anesthetized dogs. Each animal was studied during ventilation with room air and again during ventilation with gas mixtures of appropriate concentrations; 24 hr separated the study periods. AS was infused intravenously at a rate of 5 μg/kg per min.

Authors

John F. Williams Jr., Daniel L. Boyd, John F. Border

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Other pages:
1885 1886 1887 1888 1889 1890 1891 1892 1893 1894