Metabolisms

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1093-1103. https://doi.org/10.1172/JCI15693.
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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

Abstract

Research Article

Authors

I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord, Julia M. Keogh, Elizabeth Lawrence, Chizo Agwu, Veronica Sanna, Susan A. Jebb, Francesco Perna, Silvia Fontana, Robert I. Lechler, Alex M. DePaoli, Stephen O’Rahilly

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1191-1200. https://doi.org/10.1172/JCI16309.
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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Abstract

Research Article

Authors

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, Erik G. Lund, Ulla Andersson, Gertrud Schuster, Ingemar Björkhem, David W. Russell, Gosta Eggertsen

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Using SORLA to sort out human obesity
Vanessa Schmidt and colleagues demonstrate that the intracellular sorting receptor SORLA is an important regulator of lipid metabolism…
Published June 20, 2016
Scientific Show StopperMetabolism
Intracellular calcium leak recasts β cell landscape
Gaetano Santulli and colleagues reveal that RyR2 calcium channels in pancreatic β cells mediate insulin release and glucose homeostasis…
Published April 6, 2015
Scientific Show StopperMetabolism
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