Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Clinical innovation and scientific progress in GLP-1 medicine (Nov 2025)
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Issue published August 1, 2002 Previous issue | Next issue

  • Volume 110, Issue 3
Go to section:
  • In this issue
  • Spotlight
  • Perspectives
  • Commentaries
  • Research Articles
  • Corrigendum
In this issue
In This Issue
View: Text | PDF

In This Issue

  • Text
  • PDF
Abstract

Authors

×
Spotlight
Isoprenoids as mediators of the biological effects of statins
James K. Liao
James K. Liao
View: Text | PDF

Isoprenoids as mediators of the biological effects of statins

  • Text
  • PDF
Abstract

Spotlight

Authors

James K. Liao

×
Perspectives
Cancer vaccines: progress reveals new complexities
Zhiya Yu, Nicholas P. Restifo
Zhiya Yu, Nicholas P. Restifo
View: Text | PDF

Cancer vaccines: progress reveals new complexities

  • Text
  • PDF
Abstract

Perspective

Authors

Zhiya Yu, Nicholas P. Restifo

×

Immunogenetics and the design of Plasmodium falciparum vaccines for use in malaria-endemic populations
Magdalena Plebanski, Owen Proudfoot, Dodie Pouniotis, Ross L. Coppel, Vasso Apostolopoulos, Graham Flannery
Magdalena Plebanski, Owen Proudfoot, Dodie Pouniotis, Ross L. Coppel, Vasso Apostolopoulos, Graham Flannery
View: Text | PDF

Immunogenetics and the design of Plasmodium falciparum vaccines for use in malaria-endemic populations

  • Text
  • PDF
Abstract

Perspective

Authors

Magdalena Plebanski, Owen Proudfoot, Dodie Pouniotis, Ross L. Coppel, Vasso Apostolopoulos, Graham Flannery

×
Commentaries
Optimizing hematopoietic stem cell engraftment: a novel role for thrombopoietin
Catherine M. Verfaillie
Catherine M. Verfaillie
View: Text | PDF

Optimizing hematopoietic stem cell engraftment: a novel role for thrombopoietin

  • Text
  • PDF
Abstract

Commentary

Authors

Catherine M. Verfaillie

×

Renal interstitial fibrosis: Remembrance of things past?
Doris Herzlinger
Doris Herzlinger
View: Text | PDF

Renal interstitial fibrosis: Remembrance of things past?

  • Text
  • PDF
Abstract

Commentary

Authors

Doris Herzlinger

×

Maternal-fetal conflict — lessons from a transgene
Linda C. Giudice
Linda C. Giudice
View: Text | PDF

Maternal-fetal conflict — lessons from a transgene

  • Text
  • PDF
Abstract

Commentary

Authors

Linda C. Giudice

×
Research Articles
Stem cell factor stimulates neurogenesis in vitro and in vivo
Kunlin Jin, Xiao Ou Mao, Yunjuan Sun, Lin Xie, David A. Greenberg
Kunlin Jin, Xiao Ou Mao, Yunjuan Sun, Lin Xie, David A. Greenberg
View: Text | PDF

Stem cell factor stimulates neurogenesis in vitro and in vivo

  • Text
  • PDF
Abstract

Research Article

Authors

Kunlin Jin, Xiao Ou Mao, Yunjuan Sun, Lin Xie, David A. Greenberg

×

Type I interferons regulate inflammatory cell trafficking and macrophage inflammatory protein 1α delivery to the liver
Thais P. Salazar-Mather, Casey A. Lewis, Christine A. Biron
Thais P. Salazar-Mather, Casey A. Lewis, Christine A. Biron
View: Text | PDF

Type I interferons regulate inflammatory cell trafficking and macrophage inflammatory protein 1α delivery to the liver

  • Text
  • PDF
Abstract

Research Article

Authors

Thais P. Salazar-Mather, Casey A. Lewis, Christine A. Biron

×

Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
Masanori Ozaki, Seinosuke Kawashima, Tomoya Yamashita, Tetsuaki Hirase, Masayuki Namiki, Nobutaka Inoue, Ken-ichi Hirata, Hiroyuki Yasui, Hiromu Sakurai, Yuichi Yoshida, Masahiro Masada, Mitsuhiro Yokoyama
Masanori Ozaki, Seinosuke Kawashima, Tomoya Yamashita, Tetsuaki Hirase, Masayuki Namiki, Nobutaka Inoue, Ken-ichi Hirata, Hiroyuki Yasui, Hiromu Sakurai, Yuichi Yoshida, Masahiro Masada, Mitsuhiro Yokoyama
View: Text | PDF

Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice

  • Text
  • PDF
Abstract

Research Article

Authors

Masanori Ozaki, Seinosuke Kawashima, Tomoya Yamashita, Tetsuaki Hirase, Masayuki Namiki, Nobutaka Inoue, Ken-ichi Hirata, Hiroyuki Yasui, Hiromu Sakurai, Yuichi Yoshida, Masahiro Masada, Mitsuhiro Yokoyama

×

Evidence that fibroblasts derive from epithelium during tissue fibrosis
Masayuki Iwano, David Plieth, Theodore M. Danoff, Chengsen Xue, Hirokazu Okada, Eric G. Neilson
Masayuki Iwano, David Plieth, Theodore M. Danoff, Chengsen Xue, Hirokazu Okada, Eric G. Neilson
View: Text | PDF

Evidence that fibroblasts derive from epithelium during tissue fibrosis

  • Text
  • PDF
Abstract

Research Article

Authors

Masayuki Iwano, David Plieth, Theodore M. Danoff, Chengsen Xue, Hirokazu Okada, Eric G. Neilson

×

Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival
Dinesh S. Rao, Teresa S. Hyun, Priti D. Kumar, Ikuko F. Mizukami, Mark A. Rubin, Peter C. Lucas, Martin G. Sanda, Theodora S. Ross
Dinesh S. Rao, Teresa S. Hyun, Priti D. Kumar, Ikuko F. Mizukami, Mark A. Rubin, Peter C. Lucas, Martin G. Sanda, Theodora S. Ross
View: Text | PDF

Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival

  • Text
  • PDF
Abstract

Research Article

Authors

Dinesh S. Rao, Teresa S. Hyun, Priti D. Kumar, Ikuko F. Mizukami, Mark A. Rubin, Peter C. Lucas, Martin G. Sanda, Theodora S. Ross

×

Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity
Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Rieko Arakaki, Kouichi Ogawa, Ichiro Saito, Nobuhiko Katunuma, Yoshio Hayashi
Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Rieko Arakaki, Kouichi Ogawa, Ichiro Saito, Nobuhiko Katunuma, Yoshio Hayashi
View: Text | PDF

Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

  • Text
  • PDF
Abstract

Research Article

Authors

Kaoru Saegusa, Naozumi Ishimaru, Kumiko Yanagi, Rieko Arakaki, Kouichi Ogawa, Ichiro Saito, Nobuhiko Katunuma, Yoshio Hayashi

×

In vivo bradykinin B2 receptor activation reduces renal fibrosis
Joost P. Schanstra, Eric Neau, Pascale Drogoz, Miguel A. Arevalo Gomez, José Miguel Lopez Novoa, Denis Calise, Christiane Pecher, Michael Bader, Jean-Pierre Girolami, Jean-Loup Bascands
Joost P. Schanstra, Eric Neau, Pascale Drogoz, Miguel A. Arevalo Gomez, José Miguel Lopez Novoa, Denis Calise, Christiane Pecher, Michael Bader, Jean-Pierre Girolami, Jean-Loup Bascands
View: Text | PDF

In vivo bradykinin B2 receptor activation reduces renal fibrosis

  • Text
  • PDF
Abstract

Research Article

Authors

Joost P. Schanstra, Eric Neau, Pascale Drogoz, Miguel A. Arevalo Gomez, José Miguel Lopez Novoa, Denis Calise, Christiane Pecher, Michael Bader, Jean-Pierre Girolami, Jean-Loup Bascands

×

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
Martin Tristani-Firouzi, Judy L. Jensen, Matthew R. Donaldson, Valeria Sansone, Giovanni Meola, Angelika Hahn, Said Bendahhou, Hubert Kwiecinski, Anna Fidzianska, Nikki Plaster, Ying-Hui Fu, Louis J. Ptacek, Rabi Tawil
Martin Tristani-Firouzi, Judy L. Jensen, Matthew R. Donaldson, Valeria Sansone, Giovanni Meola, Angelika Hahn, Said Bendahhou, Hubert Kwiecinski, Anna Fidzianska, Nikki Plaster, Ying-Hui Fu, Louis J. Ptacek, Rabi Tawil
View: Text | PDF

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)

  • Text
  • PDF
Abstract

Research Article

Authors

Martin Tristani-Firouzi, Judy L. Jensen, Matthew R. Donaldson, Valeria Sansone, Giovanni Meola, Angelika Hahn, Said Bendahhou, Hubert Kwiecinski, Anna Fidzianska, Nikki Plaster, Ying-Hui Fu, Louis J. Ptacek, Rabi Tawil

×

Thrombopoietin expands hematopoietic stem cells after transplantation
Norma Fox, Greg Priestley, Thalia Papayannopoulou, Kenneth Kaushansky
Norma Fox, Greg Priestley, Thalia Papayannopoulou, Kenneth Kaushansky
View: Text | PDF

Thrombopoietin expands hematopoietic stem cells after transplantation

  • Text
  • PDF
Abstract

Research Article

Authors

Norma Fox, Greg Priestley, Thalia Papayannopoulou, Kenneth Kaushansky

×

Adenosine kinase inhibition promotes survival of fetal adenosine deaminase–deficient thymocytes by blocking dATP accumulation
C. Justin Van De Wiele, James G. Vaughn, Michael R. Blackburn, Catherine A. Ledent, Marlene Jacobson, Hong Jiang, Linda F. Thompson
C. Justin Van De Wiele, James G. Vaughn, Michael R. Blackburn, Catherine A. Ledent, Marlene Jacobson, Hong Jiang, Linda F. Thompson
View: Text | PDF

Adenosine kinase inhibition promotes survival of fetal adenosine deaminase–deficient thymocytes by blocking dATP accumulation

  • Text
  • PDF
Abstract

Research Article

Authors

C. Justin Van De Wiele, James G. Vaughn, Michael R. Blackburn, Catherine A. Ledent, Marlene Jacobson, Hong Jiang, Linda F. Thompson

×

Transcriptional control of viral gene therapy by cisplatin
James O. Park, Carlos A. Lopez, Vinay K. Gupta, Charles K. Brown, Helena J. Mauceri, Thomas E. Darga, Abdullah Manan, Samuel Hellman, Mitchell C. Posner, Donald W. Kufe, Ralph R. Weichselbaum
James O. Park, Carlos A. Lopez, Vinay K. Gupta, Charles K. Brown, Helena J. Mauceri, Thomas E. Darga, Abdullah Manan, Samuel Hellman, Mitchell C. Posner, Donald W. Kufe, Ralph R. Weichselbaum
View: Text | PDF

Transcriptional control of viral gene therapy by cisplatin

  • Text
  • PDF
Abstract

Research Article

Authors

James O. Park, Carlos A. Lopez, Vinay K. Gupta, Charles K. Brown, Helena J. Mauceri, Thomas E. Darga, Abdullah Manan, Samuel Hellman, Mitchell C. Posner, Donald W. Kufe, Ralph R. Weichselbaum

×

Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice
Paul A. Crossey, Claire C. Pillai, John P. Miell
Paul A. Crossey, Claire C. Pillai, John P. Miell
View: Text | PDF

Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice

  • Text
  • PDF
Abstract

Research Article

Authors

Paul A. Crossey, Claire C. Pillai, John P. Miell

×
Corrigendum
Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Qi Zhonghua, Chuan-Ming Hao, Robert I. Langenbach, Richard M. Breyer, Reyadh Redha, Jason D. Morrow, Matthew D. Breyer
Qi Zhonghua, Chuan-Ming Hao, Robert I. Langenbach, Richard M. Breyer, Reyadh Redha, Jason D. Morrow, Matthew D. Breyer
View: Text | PDF | Amended Article

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

  • Text
  • PDF
Abstract

Corrigendum

Authors

Qi Zhonghua, Chuan-Ming Hao, Robert I. Langenbach, Richard M. Breyer, Reyadh Redha, Jason D. Morrow, Matthew D. Breyer

×
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts