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Issue published October 15, 1997 Previous issue | Next issue

  • Volume 100, Issue 8
Go to section:
  • Editorial
  • Correction
  • Research Articles
Editorial
SREBPs, membrane lipid biosynthesis, and fatty acids.
T Y Chang
T Y Chang
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1905-1906. https://doi.org/10.1172/JCI119720.
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SREBPs, membrane lipid biosynthesis, and fatty acids.

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Editorial

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T Y Chang

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Correction
Correction
/articles/view/119655C1
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2141-2141. https://doi.org/10.1172/JCI119655C1.
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Correction

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Research Articles
A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.
A Görlach, … , S J Chanock, J T Curnutte
A Görlach, … , S J Chanock, J T Curnutte
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1907-1918. https://doi.org/10.1172/JCI119721.
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A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease.

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Research Article

Authors

A Görlach, P L Lee, J Roesler, P J Hopkins, B Christensen, E D Green, S J Chanock, J T Curnutte

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Myocardial insulin resistance in patients with syndrome X.
H E Botker, … , J P Bagger, T T Nielsen
H E Botker, … , J P Bagger, T T Nielsen
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1919-1927. https://doi.org/10.1172/JCI119722.
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Myocardial insulin resistance in patients with syndrome X.

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Research Article

Authors

H E Botker, N Moller, O Schmitz, J P Bagger, T T Nielsen

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Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum.
A T Blikslager, … , J M Rhoads, R A Argenzio
A T Blikslager, … , J M Rhoads, R A Argenzio
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1928-1933. https://doi.org/10.1172/JCI119723.
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Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum.

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Research Article

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A T Blikslager, M C Roberts, J M Rhoads, R A Argenzio

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Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice.
D D Woo, … , N Khatibi, P Olsen
D D Woo, … , N Khatibi, P Olsen
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1934-1940. https://doi.org/10.1172/JCI119724.
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Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice.

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D D Woo, D K Nguyen, N Khatibi, P Olsen

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Hypercalcemia stimulates expression of intrarenal phospholipase A2 and prostaglandin H synthase-2 in rats. Role of angiotensin II AT1 receptors.
H Mangat, … , L N Peterson, K D Burns
H Mangat, … , L N Peterson, K D Burns
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1941-1950. https://doi.org/10.1172/JCI119725.
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Hypercalcemia stimulates expression of intrarenal phospholipase A2 and prostaglandin H synthase-2 in rats. Role of angiotensin II AT1 receptors.

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H Mangat, L N Peterson, K D Burns

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Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.
H Zhang, … , J M Wilson, Y Chen
H Zhang, … , J M Wilson, Y Chen
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1951-1957. https://doi.org/10.1172/JCI119726.
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Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

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Authors

H Zhang, Y Yang, J L Horton, E B Samoilova, T A Judge, L A Turka, J M Wilson, Y Chen

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Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice.
M C Colbert, … , R Klevitsky, J Robbins
M C Colbert, … , R Klevitsky, J Robbins
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1958-1968. https://doi.org/10.1172/JCI119727.
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Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice.

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M C Colbert, D G Hall, T R Kimball, S A Witt, J N Lorenz, M L Kirby, T E Hewett, R Klevitsky, J Robbins

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Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome.
J D Lay, … , M E Kadin, I J Su
J D Lay, … , M E Kadin, I J Su
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1969-1979. https://doi.org/10.1172/JCI119728.
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Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome.

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Research Article

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J D Lay, C J Tsao, J Y Chen, M E Kadin, I J Su

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Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.
S C Lin, … , E Abe, S C Manolagas
S C Lin, … , E Abe, S C Manolagas
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1980-1990. https://doi.org/10.1172/JCI119729.
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Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.

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Research Article

Authors

S C Lin, T Yamate, Y Taguchi, V Z Borba, G Girasole, C A O'Brien, T Bellido, E Abe, S C Manolagas

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Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy.
Q Li, … , R Baserga, P Anversa
Q Li, … , R Baserga, P Anversa
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):1991-1999. https://doi.org/10.1172/JCI119730.
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Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy.

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Research Article

Authors

Q Li, B Li, X Wang, A Leri, K P Jana, Y Liu, J Kajstura, R Baserga, P Anversa

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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist.
M Vincent, … , G M Lathrop, J Sassard
M Vincent, … , G M Lathrop, J Sassard
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2000-2006. https://doi.org/10.1172/JCI119731.
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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist.

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M Vincent, N J Samani, D Gauguier, J R Thompson, G M Lathrop, J Sassard

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Insulin modulation of an endothelial nitric oxide component present in the alpha2- and beta-adrenergic responses in human forearm.
G Lembo, … , D Fontana, B Trimarco
G Lembo, … , D Fontana, B Trimarco
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2007-2014. https://doi.org/10.1172/JCI119732.
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Insulin modulation of an endothelial nitric oxide component present in the alpha2- and beta-adrenergic responses in human forearm.

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Authors

G Lembo, G Iaccarino, C Vecchione, E Barbato, R Izzo, D Fontana, B Trimarco

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A non-MHC locus essential for autoimmune type I diabetes in the Komeda Diabetes-Prone rat.
N Yokoi, … , T Serikawa, K Komeda
N Yokoi, … , T Serikawa, K Komeda
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2015-2021. https://doi.org/10.1172/JCI119733.
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A non-MHC locus essential for autoimmune type I diabetes in the Komeda Diabetes-Prone rat.

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Research Article

Authors

N Yokoi, M Kanazawa, K Kitada, A Tanaka, Y Kanazawa, S Suda, H Ito, T Serikawa, K Komeda

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Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury.
C Gerard, … , B Lu, M Steer
C Gerard, … , B Lu, M Steer
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2022-2027. https://doi.org/10.1172/JCI119734.
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Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury.

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Authors

C Gerard, J L Frossard, M Bhatia, A Saluja, N P Gerard, B Lu, M Steer

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Localization of distinct F2-isoprostanes in human atherosclerotic lesions.
D Praticò, … , F Violi, G A FitzGerald
D Praticò, … , F Violi, G A FitzGerald
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2028-2034. https://doi.org/10.1172/JCI119735.
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Localization of distinct F2-isoprostanes in human atherosclerotic lesions.

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Research Article

Authors

D Praticò, L Iuliano, A Mauriello, L Spagnoli, J A Lawson, J Rokach, J Maclouf, F Violi, G A FitzGerald

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Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis.
L L Shears, … , A Lizonova, S M Pham
L L Shears, … , A Lizonova, S M Pham
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2035-2042. https://doi.org/10.1172/JCI119736.
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Inducible nitric oxide synthase suppresses the development of allograft arteriosclerosis.

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Research Article

Authors

L L Shears, N Kawaharada, E Tzeng, T R Billiar, S C Watkins, I Kovesdi, A Lizonova, S M Pham

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Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways.
A Blauvelt, … , R Yarchoan, S I Katz
A Blauvelt, … , R Yarchoan, S I Katz
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2043-2053. https://doi.org/10.1172/JCI119737.
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Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways.

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Research Article

Authors

A Blauvelt, H Asada, M W Saville, V Klaus-Kovtun, D J Altman, R Yarchoan, S I Katz

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Pertussis toxin-sensitive G proteins as mediators of the signal transduction pathways activated by cytomegalovirus infection of smooth muscle cells.
T Shibutani, … , J Moss, S E Epstein
T Shibutani, … , J Moss, S E Epstein
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2054-2061. https://doi.org/10.1172/JCI119738.
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Pertussis toxin-sensitive G proteins as mediators of the signal transduction pathways activated by cytomegalovirus infection of smooth muscle cells.

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Research Article

Authors

T Shibutani, T M Johnson, Z X Yu, V J Ferrans, J Moss, S E Epstein

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Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease.
L S Toy, … , S Honig, L Mayer
L S Toy, … , S Honig, L Mayer
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2062-2071. https://doi.org/10.1172/JCI119739.
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Defective expression of gp180, a novel CD8 ligand on intestinal epithelial cells, in inflammatory bowel disease.

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Research Article

Authors

L S Toy, X Y Yio, A Lin, S Honig, L Mayer

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.
P Lin, … , P S Rao, K Peters
P Lin, … , P S Rao, K Peters
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2072-2078. https://doi.org/10.1172/JCI119740.
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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.

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Research Article

Authors

P Lin, P Polverini, M Dewhirst, S Shan, P S Rao, K Peters

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A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen-mediated platelet aggregation.
T M Chiang, A H Kang
T M Chiang, A H Kang
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2079-2084. https://doi.org/10.1172/JCI119741.
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A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen-mediated platelet aggregation.

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Research Article

Authors

T M Chiang, A H Kang

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Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor.
C Weber, T A Springer
C Weber, T A Springer
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2085-2093. https://doi.org/10.1172/JCI119742.
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Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor.

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Authors

C Weber, T A Springer

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Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.
F Delaunay, … , S Efendic, S Okret
F Delaunay, … , S Efendic, S Okret
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2094-2098. https://doi.org/10.1172/JCI119743.
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Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids.

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Research Article

Authors

F Delaunay, A Khan, A Cintra, B Davani, Z C Ling, A Andersson, C G Ostenson, J Gustafsson, S Efendic, S Okret

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Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.
F M Munoz, … , A L Beaudet, S L Kaplan
F M Munoz, … , A L Beaudet, S L Kaplan
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2099-2106. https://doi.org/10.1172/JCI119744.
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Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.

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Authors

F M Munoz, E P Hawkins, D C Bullard, A L Beaudet, S L Kaplan

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Cellular mechanisms mediating rat renal microvascular constriction by angiotensin II.
T Takenaka, … , T Nagahama, T Saruta
T Takenaka, … , T Nagahama, T Saruta
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2107-2114. https://doi.org/10.1172/JCI119745.
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Cellular mechanisms mediating rat renal microvascular constriction by angiotensin II.

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Research Article

Authors

T Takenaka, H Suzuki, K Fujiwara, Y Kanno, Y Ohno, K Hayashi, T Nagahama, T Saruta

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Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.
H Shimano, … , M S Brown, J D Horton
H Shimano, … , M S Brown, J D Horton
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2115-2124. https://doi.org/10.1172/JCI119746.
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Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

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Research Article

Authors

H Shimano, I Shimomura, R E Hammer, J Herz, J L Goldstein, M S Brown, J D Horton

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Responsiveness of muscle protein synthesis to growth hormone administration in HIV-infected individuals declines with severity of disease.
M A McNurlan, … , J Fuhrer, M C Gelato
M A McNurlan, … , J Fuhrer, M C Gelato
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2125-2132. https://doi.org/10.1172/JCI119747.
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Responsiveness of muscle protein synthesis to growth hormone administration in HIV-infected individuals declines with severity of disease.

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Research Article

Authors

M A McNurlan, P J Garlick, R T Steigbigel, K A DeCristofaro, R A Frost, C H Lang, R W Johnson, A M Santasier, C J Cabahug, J Fuhrer, M C Gelato

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Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis.
W A Franklin, … , D M Ritchey, Y E Miller
W A Franklin, … , D M Ritchey, Y E Miller
Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2133-2137. https://doi.org/10.1172/JCI119748.
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Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis.

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Research Article

Authors

W A Franklin, A F Gazdar, J Haney, I I Wistuba, F G La Rosa, T Kennedy, D M Ritchey, Y E Miller

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