Oncology

IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells
Robin Parihar, … , Yan Hu, William E. Carson
Robin Parihar, … , Yan Hu, William E. Carson
Published October 1, 2002
Citation Information: J Clin Invest. 2002;110(7):983-992. https://doi.org/10.1172/JCI15950.
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IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells

Abstract

Research Article

Authors

Robin Parihar, Julie Dierksheide, Yan Hu, William E. Carson

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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
Sabina Signoretti, … , Massimo Loda, Michele Pagano
Sabina Signoretti, … , Massimo Loda, Michele Pagano
Published September 1, 2002
Citation Information: J Clin Invest. 2002;110(5):633-641. https://doi.org/10.1172/JCI15795.
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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Abstract

Research Article

Authors

Sabina Signoretti, Lucia Di Marcotullio, Andrea Richardson, Sridhar Ramaswamy, Beth Isaac, Montserrat Rue, Franco Monti, Massimo Loda, Michele Pagano

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An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis
Anindita Bhoumik, … , Shu-Hsia Chen, Ze’ev Ronai
Anindita Bhoumik, … , Shu-Hsia Chen, Ze’ev Ronai
Published September 1, 2002
Citation Information: J Clin Invest. 2002;110(5):643-650 . https://doi.org/10.1172/JCI16081.
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An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis

Abstract

Research Article

Authors

Anindita Bhoumik, Tian-Gui Huang, Vladimir Ivanov, Lisa Gangi, Rui F. Qiao, Savio L.C. Woo, Shu-Hsia Chen, Ze’ev Ronai

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E2F8 keeps liver cancer at bay
Alain de Bruin, Gustavo Leone, and colleagues find that the E2F8-mediated transcriptional repression in the developing liver suppresses hepatocellular carcinoma later in life …
Published July 25, 2016
Scientific Show StopperOncology
AIDing and abetting UV-independent skin cancer
Taichiro Nonaka and colleagues find that AID plays a role in the development of inflammation-driven, non-UV skin cancer
Published March 14, 2016
Scientific Show StopperOncology
CD37 keeps B cell lymphoma at bay
Charlotte de Winde, Sharon Veenbergen, and colleagues demonstrate that loss of CD37 expression relieves SOCS3-mediated suppression of IL-6 signaling and supports the development of B cell lymphoma…
Published January 19, 2016
Scientific Show StopperOncology
Maintaining endometrial epithelial barrier function
Jessica Bowser and colleagues identify a mechanism by which loss of CD73 promotes endometrial cancer progression…
Published December 7, 2015
Scientific Show StopperOncology
Sleuthing out the cellular source of hepatocellular carcinoma
Xueru Mu, Regina Español-Suñer, and colleagues show that tumors in murine hepatocellular carcinoma models are derived from hepatocytes and not from other liver resident cells …
Published September 8, 2015
Scientific Show StopperOncology
Live animal imaging in the far red
Ming Zhang and colleagues developed a far-red-absorbing reporter/probe system that can be used to image live animals and overcomes imaging limitations associated with conventional systems that use lower wavelengths of light…
Published September 8, 2015
Scientific Show StopperTechnical AdvanceOncology
Cancer cells fight off stress with ATF4
Souvik Dey, Carly Sayers, and colleagues reveal that activation of heme oxygenase 1 by ATF4 protects cancer cells from ECM detachment-induced death and promotes metastasis…
Published May 26, 2015
Scientific Show StopperOncology
Smothering Von Hippel-Lindau syndrome-associated phenotypes
Ana Metelo and colleagues demonstrate that specific inhibition of HIF2a ameliorates VHL-associated phenotypes and improves survival in a zebrafish model of disease…
Published April 13, 2015
Scientific Show StopperOncology
Blazing the trail for metastasis
Jill Westcott, Amanda Prechtl, and colleagues identify an epigenetically distinct population of breast cancer cells that promotes collective invasion…
Published April 6, 2015
Scientific Show StopperOncology
Dynamic focal adhesions
Wies van Roosmalen, Sylvia E. Le Dévédec, and colleagues screen for genes that alter cancer cell migration and demonstrate that SRPK1 promotes metastasis...
Published March 16, 2015
Scientific Show StopperOncology
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