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Issue published October 1, 2002 Previous issue | Next issue

  • Volume 110, Issue 7
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  • In this issue
  • Spotlight
  • Perspectives
  • Commentaries
  • Research Articles
In this issue
In This Issue
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In This Issue

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Abstract

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Spotlight
Lessons from viral manipulation of protein disposal pathways
Margo H. Furman, Hidde L. Ploegh
Margo H. Furman, Hidde L. Ploegh
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Lessons from viral manipulation of protein disposal pathways

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Spotlight

Authors

Margo H. Furman, Hidde L. Ploegh

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Perspectives
High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex
Colin Jefcoate
Colin Jefcoate
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High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex

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Abstract

Perspective

Authors

Colin Jefcoate

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Intracellular cholesterol transport
Frederick R. Maxfield, Daniel Wüstner
Frederick R. Maxfield, Daniel Wüstner
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Intracellular cholesterol transport

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Abstract

Perspective

Authors

Frederick R. Maxfield, Daniel Wüstner

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Regulation and mechanisms of macrophage cholesterol efflux
Alan R. Tall, Philippe Costet, Nan Wang
Alan R. Tall, Philippe Costet, Nan Wang
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Regulation and mechanisms of macrophage cholesterol efflux

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Abstract

Perspective

Authors

Alan R. Tall, Philippe Costet, Nan Wang

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Consequences of cellular cholesterol accumulation: basic concepts and physiological implications
Ira Tabas
Ira Tabas
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Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

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Abstract

Perspective

Authors

Ira Tabas

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Commentaries
Endothelial integrins and angiogenesis: not so simple anymore
Dean Sheppard
Dean Sheppard
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Endothelial integrins and angiogenesis: not so simple anymore

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Commentary

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Dean Sheppard

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Anxiolytic drug targets: beyond the usual suspects
Joshua A. Gordon
Joshua A. Gordon
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Anxiolytic drug targets: beyond the usual suspects

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Commentary

Authors

Joshua A. Gordon

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Antineutrophil cytoplasmic antibody and vasculitis: much more than a disease marker
Vivette D’Agati
Vivette D’Agati
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Antineutrophil cytoplasmic antibody and vasculitis: much more than a disease marker

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Commentary

Authors

Vivette D’Agati

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Research Articles
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
Dipak Panigrahy, Samuel Singer, Lucy Q. Shen, Catherine E. Butterfield, Deborah A. Freedman, Emy J. Chen, Marsha A. Moses, Susan Kilroy, Stefan Duensing, Christopher Fletcher, Jonathan A. Fletcher, Lynn Hlatky, Philip Hahnfeldt, Judah Folkman, Arja Kaipainen
Dipak Panigrahy, Samuel Singer, Lucy Q. Shen, Catherine E. Butterfield, Deborah A. Freedman, Emy J. Chen, Marsha A. Moses, Susan Kilroy, Stefan Duensing, Christopher Fletcher, Jonathan A. Fletcher, Lynn Hlatky, Philip Hahnfeldt, Judah Folkman, Arja Kaipainen
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PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis

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Research Article

Authors

Dipak Panigrahy, Samuel Singer, Lucy Q. Shen, Catherine E. Butterfield, Deborah A. Freedman, Emy J. Chen, Marsha A. Moses, Susan Kilroy, Stefan Duensing, Christopher Fletcher, Jonathan A. Fletcher, Lynn Hlatky, Philip Hahnfeldt, Judah Folkman, Arja Kaipainen

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Inhibition of endothelial cell survival and angiogenesis by protein kinase A
Semi Kim, Manjiri Bakre, Hong Yin, Judith A. Varner
Semi Kim, Manjiri Bakre, Hong Yin, Judith A. Varner
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Inhibition of endothelial cell survival and angiogenesis by protein kinase A

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Research Article

Authors

Semi Kim, Manjiri Bakre, Hong Yin, Judith A. Varner

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Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions
Gal Markel, Dana Wolf, Jacob Hanna, Roi Gazit, Debra Goldman-Wohl, Yuval Lavy, Simcha Yagel, Ofer Mandelboim
Gal Markel, Dana Wolf, Jacob Hanna, Roi Gazit, Debra Goldman-Wohl, Yuval Lavy, Simcha Yagel, Ofer Mandelboim
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Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions

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Research Article

Authors

Gal Markel, Dana Wolf, Jacob Hanna, Roi Gazit, Debra Goldman-Wohl, Yuval Lavy, Simcha Yagel, Ofer Mandelboim

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Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice
Hong Xiao, Peter Heeringa, Peiqi Hu, Zhi Liu, Minglang Zhao, Yasuaki Aratani, Nobuyo Maeda, Ronald J. Falk, J. Charles Jennette
Hong Xiao, Peter Heeringa, Peiqi Hu, Zhi Liu, Minglang Zhao, Yasuaki Aratani, Nobuyo Maeda, Ronald J. Falk, J. Charles Jennette
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Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice

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Research Article

Authors

Hong Xiao, Peter Heeringa, Peiqi Hu, Zhi Liu, Minglang Zhao, Yasuaki Aratani, Nobuyo Maeda, Ronald J. Falk, J. Charles Jennette

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The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II
Lin Wang, Carol J. Soroka, James L. Boyer
Lin Wang, Carol J. Soroka, James L. Boyer
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The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II

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Research Article

Authors

Lin Wang, Carol J. Soroka, James L. Boyer

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Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms
Kathryn G. Schuff, Shane T. Hentges, Michele A. Kelly, Nadine Binart, Paul A. Kelly, P. Michael Iuvone, Sylvia L. Asa, Malcolm J. Low
Kathryn G. Schuff, Shane T. Hentges, Michele A. Kelly, Nadine Binart, Paul A. Kelly, P. Michael Iuvone, Sylvia L. Asa, Malcolm J. Low
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Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms

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Research Article

Authors

Kathryn G. Schuff, Shane T. Hentges, Michele A. Kelly, Nadine Binart, Paul A. Kelly, P. Michael Iuvone, Sylvia L. Asa, Malcolm J. Low

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IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells
Robin Parihar, Julie Dierksheide, Yan Hu, William E. Carson
Robin Parihar, Julie Dierksheide, Yan Hu, William E. Carson
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IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells

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Research Article

Authors

Robin Parihar, Julie Dierksheide, Yan Hu, William E. Carson

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Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia
Kristin Synnestvedt, Glenn T. Furuta, Katrina M. Comerford, Nancy Louis, Jorn Karhausen, Holger K. Eltzschig, Karl R. Hansen, Linda F. Thompson, Sean P. Colgan
Kristin Synnestvedt, Glenn T. Furuta, Katrina M. Comerford, Nancy Louis, Jorn Karhausen, Holger K. Eltzschig, Karl R. Hansen, Linda F. Thompson, Sean P. Colgan
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Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

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Research Article

Authors

Kristin Synnestvedt, Glenn T. Furuta, Katrina M. Comerford, Nancy Louis, Jorn Karhausen, Holger K. Eltzschig, Karl R. Hansen, Linda F. Thompson, Sean P. Colgan

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Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cε
Clyde W. Hodge, Jacob Raber, Thomas McMahon, Helen Walter, Ana Maria Sanchez-Perez, M. Foster Olive, Kristin Mehmert, A. Leslie Morrow, Robert O. Messing
Clyde W. Hodge, Jacob Raber, Thomas McMahon, Helen Walter, Ana Maria Sanchez-Perez, M. Foster Olive, Kristin Mehmert, A. Leslie Morrow, Robert O. Messing
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Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cε

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Abstract

Research Article

Authors

Clyde W. Hodge, Jacob Raber, Thomas McMahon, Helen Walter, Ana Maria Sanchez-Perez, M. Foster Olive, Kristin Mehmert, A. Leslie Morrow, Robert O. Messing

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Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor
Shouhong Xuan, Tadahiro Kitamura, Jun Nakae, Katerina Politi, Yoshiaki Kido, Peter E. Fisher, Manrico Morroni, Saverio Cinti, Morris F. White, Pedro L. Herrera, Domenico Accili, Argiris Efstratiadis
Shouhong Xuan, Tadahiro Kitamura, Jun Nakae, Katerina Politi, Yoshiaki Kido, Peter E. Fisher, Manrico Morroni, Saverio Cinti, Morris F. White, Pedro L. Herrera, Domenico Accili, Argiris Efstratiadis
View: Text | PDF

Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor

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Abstract

Research Article

Authors

Shouhong Xuan, Tadahiro Kitamura, Jun Nakae, Katerina Politi, Yoshiaki Kido, Peter E. Fisher, Manrico Morroni, Saverio Cinti, Morris F. White, Pedro L. Herrera, Domenico Accili, Argiris Efstratiadis

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Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23
Edwin Liu, Hiroaki Moriyama, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, Fred D. Finkelman, George S. Eisenbarth
Edwin Liu, Hiroaki Moriyama, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, Fred D. Finkelman, George S. Eisenbarth
View: Text | PDF

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

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Abstract

Research Article

Authors

Edwin Liu, Hiroaki Moriyama, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, Fred D. Finkelman, George S. Eisenbarth

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Clinical and molecular analysis of patients with defects in μ heavy chain gene
Eduardo Lopez Granados, Andrea S. Porpiglia, Mary Beth Hogan, Nuria Matamoros, Silvia Krasovec, Claudio Pignata, C.I.E. Smith, Lennart Hammarstrom, Janne Bjorkander, Bernd H. Belohradsky, G. Fontan Casariego, M.C. Garcia Rodriguez, Mary Ellen Conley
Eduardo Lopez Granados, Andrea S. Porpiglia, Mary Beth Hogan, Nuria Matamoros, Silvia Krasovec, Claudio Pignata, C.I.E. Smith, Lennart Hammarstrom, Janne Bjorkander, Bernd H. Belohradsky, G. Fontan Casariego, M.C. Garcia Rodriguez, Mary Ellen Conley
View: Text | PDF

Clinical and molecular analysis of patients with defects in μ heavy chain gene

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Abstract

Research Article

Authors

Eduardo Lopez Granados, Andrea S. Porpiglia, Mary Beth Hogan, Nuria Matamoros, Silvia Krasovec, Claudio Pignata, C.I.E. Smith, Lennart Hammarstrom, Janne Bjorkander, Bernd H. Belohradsky, G. Fontan Casariego, M.C. Garcia Rodriguez, Mary Ellen Conley

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The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
Gaël Nicolas, Caroline Chauvet, Lydie Viatte, Jean Louis Danan, Xavier Bigard, Isabelle Devaux, Carole Beaumont, Axel Kahn, Sophie Vaulont
Gaël Nicolas, Caroline Chauvet, Lydie Viatte, Jean Louis Danan, Xavier Bigard, Isabelle Devaux, Carole Beaumont, Axel Kahn, Sophie Vaulont
View: Text | PDF

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

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Abstract

Research Article

Authors

Gaël Nicolas, Caroline Chauvet, Lydie Viatte, Jean Louis Danan, Xavier Bigard, Isabelle Devaux, Carole Beaumont, Axel Kahn, Sophie Vaulont

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Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
Annette Robichaud, Panagiota B. Stamatiou, S.-L.Catherine Jin, Nicholas Lachance, Dwight MacDonald, France Laliberté, Susana Liu, Zheng Huang, Marco Conti, Chi-Chung Chan
Annette Robichaud, Panagiota B. Stamatiou, S.-L.Catherine Jin, Nicholas Lachance, Dwight MacDonald, France Laliberté, Susana Liu, Zheng Huang, Marco Conti, Chi-Chung Chan
View: Text | PDF

Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis

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Abstract

Research Article

Authors

Annette Robichaud, Panagiota B. Stamatiou, S.-L.Catherine Jin, Nicholas Lachance, Dwight MacDonald, France Laliberté, Susana Liu, Zheng Huang, Marco Conti, Chi-Chung Chan

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