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Issue published October 15, 2002 Previous issue | Next issue

  • Volume 110, Issue 8
Go to section:
  • In this issue
  • Science and Society
  • Perspective
  • Commentaries
  • Research Articles
  • Erratum
  • Corrigendum
In this issue
In This Issue
/articles/view/119960
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1055-1055. https://doi.org/10.1172/JCI119960.
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In This Issue

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Abstract

Authors

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Science and Society
It takes a village to raise an idiot: fixing US science education
Alan Dove
Alan Dove
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1057-1060. https://doi.org/10.1172/JCI16959.
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It takes a village to raise an idiot: fixing US science education

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Science and Society

Authors

Alan Dove

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Perspective
Bacterial infectious disease control by vaccine development
Roy Curtiss III
Roy Curtiss III
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1061-1066. https://doi.org/10.1172/JCI16941.
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Bacterial infectious disease control by vaccine development

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Perspective

Authors

Roy Curtiss III

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Commentaries
Does loss of bile acid homeostasis make mice melancholy?
David D. Moore
David D. Moore
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1067-1069. https://doi.org/10.1172/JCI16943.
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Does loss of bile acid homeostasis make mice melancholy?

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Commentary

Authors

David D. Moore

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Genome-wide responses of a pathogenic bacterium to its host
David A. Relman
David A. Relman
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1071-1073. https://doi.org/10.1172/JCI16944.
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Genome-wide responses of a pathogenic bacterium to its host

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Commentary

Authors

David A. Relman

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Defective cardiac ion channels: from mutations to clinical syndromes
Colleen E. Clancy, Robert S. Kass
Colleen E. Clancy, Robert S. Kass
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1075-1077. https://doi.org/10.1172/JCI16945.
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Defective cardiac ion channels: from mutations to clinical syndromes

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Commentary

Authors

Colleen E. Clancy, Robert S. Kass

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Intestinal attraction: CCL25 functions in effector lymphocyte recruitment to the small intestine
Daniel J. Campbell, Eugene C. Butcher
Daniel J. Campbell, Eugene C. Butcher
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1079-1081. https://doi.org/10.1172/JCI16946.
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Intestinal attraction: CCL25 functions in effector lymphocyte recruitment to the small intestine

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Commentary

Authors

Daniel J. Campbell, Eugene C. Butcher

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Research Articles
Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice
Vyacheslav Y. Melnikov, … , Danica Ljubanovic, Charles L. Edelstein
Vyacheslav Y. Melnikov, … , Danica Ljubanovic, Charles L. Edelstein
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1083-1091. https://doi.org/10.1172/JCI15623.
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Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice

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Research Article

Authors

Vyacheslav Y. Melnikov, Sarah Faubel, Britta Siegmund, M. Scott Lucia, Danica Ljubanovic, Charles L. Edelstein

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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
I. Sadaf Farooqi, … , Alex M. DePaoli, Stephen O’Rahilly
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1093-1103. https://doi.org/10.1172/JCI15693.
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Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

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Research Article

Authors

I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord, Julia M. Keogh, Elizabeth Lawrence, Chizo Agwu, Veronica Sanna, Susan A. Jebb, Francesco Perna, Silvia Fontana, Robert I. Lechler, Alex M. DePaoli, Stephen O’Rahilly

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Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus
Sujin Lee, … , Bumseok Kim, Barry T. Rouse
Sujin Lee, … , Bumseok Kim, Barry T. Rouse
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1105-1111. https://doi.org/10.1172/JCI15755.
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Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus

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Research Article

Authors

Sujin Lee, Mei Zheng, Bumseok Kim, Barry T. Rouse

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CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa
Marcus Svensson, … , Gabriel Márquez, William W. Agace
Marcus Svensson, … , Gabriel Márquez, William W. Agace
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1113-1121. https://doi.org/10.1172/JCI15988.
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CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa

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Research Article

Authors

Marcus Svensson, Jan Marsal, Anna Ericsson, Laura Carramolino, Therese Brodén, Gabriel Márquez, William W. Agace

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Benzodiazepine-induced superoxide signalsB cell apoptosis: mechanistic insight and potential therapeutic utility
Neal B. Blatt, … , Anthony W. Opipari Jr., Gary D. Glick
Neal B. Blatt, … , Anthony W. Opipari Jr., Gary D. Glick
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1123-1132. https://doi.org/10.1172/JCI16029.
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Benzodiazepine-induced superoxide signalsB cell apoptosis: mechanistic insight and potential therapeutic utility

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Research Article

Authors

Neal B. Blatt, Jeffrey J. Bednarski, Roscoe E. Warner, Francesco Leonetti, Kathryn M. Johnson, Anthony Boitano, Raymond Yung, Bruce C. Richardson, Kent J. Johnson, Jonathan A. Ellman, Anthony W. Opipari Jr., Gary D. Glick

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Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis
Timothy W. Schacker, … , Cavan Reilly, Ashley T. Haase
Timothy W. Schacker, … , Cavan Reilly, Ashley T. Haase
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1133-1139. https://doi.org/10.1172/JCI16413.
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Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis

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Research Article

Authors

Timothy W. Schacker, Phuong L. Nguyen, Gregory J. Beilman, Steven Wolinsky, Matthew Larson, Cavan Reilly, Ashley T. Haase

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EphB6 crosslinking results in costimulation of T cells
Hongyu Luo, … , Yulian Wu, Jiangping Wu
Hongyu Luo, … , Yulian Wu, Jiangping Wu
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1141-1150. https://doi.org/10.1172/JCI15883.
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EphB6 crosslinking results in costimulation of T cells

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Research Article

Authors

Hongyu Luo, Guang Yu, Yulian Wu, Jiangping Wu

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mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils
Benjamin J. Staudinger, … , Patrick J. Lewis, Henry Rosen
Benjamin J. Staudinger, … , Patrick J. Lewis, Henry Rosen
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1151-1163. https://doi.org/10.1172/JCI15268.
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mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils

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Research Article

Authors

Benjamin J. Staudinger, Michele A. Oberdoerster, Patrick J. Lewis, Henry Rosen

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Delta-1 enhances marrow and thymus repopulating ability of human CD34+CD38– cord blood cells
Kohshi Ohishi, … , Barbara Varnum-Finney, Irwin D. Bernstein
Kohshi Ohishi, … , Barbara Varnum-Finney, Irwin D. Bernstein
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1165-1174. https://doi.org/10.1172/JCI16167.
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Delta-1 enhances marrow and thymus repopulating ability of human CD34+CD38– cord blood cells

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Research Article

Authors

Kohshi Ohishi, Barbara Varnum-Finney, Irwin D. Bernstein

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Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination
Lilin Wang, … , Amy Bloom, Adrian Bot
Lilin Wang, … , Amy Bloom, Adrian Bot
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1175-1184. https://doi.org/10.1172/JCI15536.
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Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination

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Abstract

Research Article

Authors

Lilin Wang, Dan Smith, Simona Bot, Luis Dellamary, Amy Bloom, Adrian Bot

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Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors
Shinya Ugawa, … , Yasuhiro Shibata, Shoichi Shimada
Shinya Ugawa, … , Yasuhiro Shibata, Shoichi Shimada
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1185-1190. https://doi.org/10.1172/JCI15709.
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Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors

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Research Article

Authors

Shinya Ugawa, Takashi Ueda, Yusuke Ishida, Makoto Nishigaki, Yasuhiro Shibata, Shoichi Shimada

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Jia Li-Hawkins, … , David W. Russell, Gosta Eggertsen
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1191-1200. https://doi.org/10.1172/JCI16309.
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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

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Research Article

Authors

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, Erik G. Lund, Ulla Andersson, Gertrud Schuster, Ingemar Björkhem, David W. Russell, Gosta Eggertsen

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Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation
Augustus O. Grant, … , Carlo Napolitano, Silvia Priori
Augustus O. Grant, … , Carlo Napolitano, Silvia Priori
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1201-1209. https://doi.org/10.1172/JCI15570.
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Long QT syndrome, Brugada syndrome, and conduction system disease are linked to a single sodium channel mutation

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Research Article

Authors

Augustus O. Grant, Michael P. Carboni, Valentina Neplioueva, C. Frank Starmer, Mirella Memmi, Carlo Napolitano, Silvia Priori

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Erratum
Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome
Duarte C. Barral, … , Kalwant S. Authi, Miguel C. Seabra
Duarte C. Barral, … , Kalwant S. Authi, Miguel C. Seabra
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1213-1213. https://doi.org/10.1172/JCI15058E1.
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Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

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Erratum

Authors

Duarte C. Barral, José S. Ramalho, Ross Anders, Alistair N. Hume, Holly J. Knapton, Tanya Tolmachova, Lucy M. Collinson, David Goulding, Kalwant S. Authi, Miguel C. Seabra

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Corrigendum
Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
Xinping Zhang, … , Randy N. Rosier, Regis J. O’Keefe
Xinping Zhang, … , Randy N. Rosier, Regis J. O’Keefe
Published October 15, 2002
Citation Information: J Clin Invest. 2002;110(8):1211-1211. https://doi.org/10.1172/JCI15681C1.
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Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair

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Abstract

Corrigendum

Authors

Xinping Zhang, Edward M. Schwarz, Donald A. Young, J. Edward Puzas, Randy N. Rosier, Regis J. O’Keefe

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