There is a strong association between obesity and type 2 diabetes (T2D); however, the majority of obese individuals do not develop T2D, supporting that genetic predisposition is an important component of the disease. Alan Attie and colleagues previo...
Published August 26, 2014

Muscle satellite cells are a rare regenerative population in adult skeletal muscle and have potential to repair damaged muscle tissue. In this episode, Simone Spuler and colleagues demonstrate that satellite cells can be successfully expanded from h...
Published August 26, 2014

Kylie Alexander and colleagues reveal that donor-derived macrophages contribute to chronic graft verses host disease…
Published August 26, 2014

Napoleone Ferrara, of the University of California, San Diego, is best known for isolating and cloning vascular endothelial growth factor (VEGF). He then built the humanized monoclonal antibody against VEGF that led to the blockbuster drugs Avastin ...
Published August 26, 2014

A research article in the September 2014 issue of the JCI identifies a microRNA-based strategy that inhibits arterial restenosis while preserving endothelial function. The authors created an adenoviral vector encoding the cyclin-dependent kinase inhibitor
Published August 18, 2014