Posts

493 items found.
Neuroscience: Recent advances
Read the latest in neuroscience in the JCI
Published February 14, 2020
IL-36γ induction underlies EGFR inhibitor-associated skin toxicity
In this episode, Lars French, Takashi K. Satoh and colleagues show that EGFR/MEK inhibitors and the commensal Cutibacterium acnes synergistically induce IL-36γ in keratinocytes, resulting in neutrophilic acneiform skin toxicities…
Published February 4, 2020
Author's Take
JCI's Conversations with Giants in Medicine: Marc Feldmann, Jacques Miller, and Max Cooper
Sir Marc Feldmann, Lasker awardee in 2003 for his role in discovering anti-TNF therapy, acts as interviewer, speaking with the two recipients of the 2019 Albert Lasker Basic Medical Research Award.
Published January 2, 2020
Conversations with Giants in Medicine
CD8+ T cell function may predict type 1 diabetes progression
In this episode, Alice Long and colleagues demonstrate a link between disease outcome in type 1 diabetes and the phenotype and function of autoreactive CD8+ T cells…
Published December 9, 2019
Author's Take
Fibronectin variant mediates smooth muscle cell phenotypic switching
In this episode, Anil Chauhan, Manish Jain, and colleagues reveal that smooth muscle cell- specific fibronectin containing an extra domain A mediates phenotypic switching and neointimal hyperplasia…
Published November 25, 2019
Author's Take
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