Posts

490 items found.
CD8+ T cell function may predict type 1 diabetes progression
In this episode, Alice Long and colleagues demonstrate a link between disease outcome in type 1 diabetes and the phenotype and function of autoreactive CD8+ T cells…
Published December 9, 2019
Author's Take
Fibronectin variant mediates smooth muscle cell phenotypic switching
In this episode, Anil Chauhan, Manish Jain, and colleagues reveal that smooth muscle cell- specific fibronectin containing an extra domain A mediates phenotypic switching and neointimal hyperplasia…
Published November 25, 2019
Author's Take
JCI's Conversations with Giants in Medicine: Elaine Fuchs
Cell biologist Elaine Fuchs of the Rockefeller University is best known for revolutionizing the molecular and genetic study of skin.
Published November 1, 2019
Conversations with Giants in Medicine
Characterization of FOXN1 mutation-mediated immune deficiency
In this episode, Nicolai van Oers and colleagues demonstrate that compound heterozygous mutations in FOXN1 result in a combined immunodeficiency in patients that is distinct Nude/SCID phenotypes…
Published October 1, 2019
Author's Take
JCI's Conversations with Giants in Medicine: Lucy Shapiro
Lucy Shapiro's insights helped launch the field of systems biology, and more recently, her work has led to the development of novel antifungal drugs.
Published August 1, 2019
Conversations with Giants in Medicine
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