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Lipid mediators of disease (Upcoming)
Cellular senescence in human disease (Apr 2018)
Fibrosis (Jan 2018)
Glia and Neurodegeneration (Sep 2017)
Transplantation (Jun 2017)
Nuclear Receptors (Apr 2017)
Metabolism and Inflammation (Jan 2017)
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Scientific Show Stoppers
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JCI This Month
468 items found.
JAK inhibitor treatment shows benefit for patients with interferonopathies
In this episode, Gina A. Montealegre Sanchez, Raphaela Goldbach-Mansky, and colleagues demonstrate that JAK1/2 inhibitor baricitinib improves clinical manifestations in a small cohort of patients with interferonopathies…
Published June 11, 2018
Published May 25, 2018
microRNA-210 skews T cell subsets to promote psoriatic inflammation
The cause of imbalances in T cell subsets-- considered a key component of psoriasis pathogenesis-- remains unclear. A study published in the JCI implicates overexpression of miR-210 in biasing T cell differentiation toward pathogenic Th1 and Th17 cells.
Published May 23, 2018
Scientific Show Stopper
REV-ERBα controls the clock in the lung
In this episode, David Ray, Marie Pariollaud and colleagues identify REV-ERBα as a critical regulator of rhythmic inflammatory responses in the lung…
Published April 30, 2018
Immune tolerance-like pathway inhibits repair following white matter injury
Stephen Back and colleagues identify an immune tolerance-like pathway that prevents repair after white matter injury…
Published April 16, 2018
Copyright © 2018
American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)
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