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468 items found.
JAK inhibitor treatment shows benefit for patients with interferonopathies
In this episode, Gina A. Montealegre Sanchez, Raphaela Goldbach-Mansky, and colleagues demonstrate that JAK1/2 inhibitor baricitinib improves clinical manifestations in a small cohort of patients with interferonopathies…
Published June 11, 2018
Author's Take
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Published May 25, 2018
microRNA-210 skews T cell subsets to promote psoriatic inflammation
The cause of imbalances in T cell subsets-- considered a key component of psoriasis pathogenesis-- remains unclear. A study published in the JCI implicates overexpression of miR-210 in biasing T cell differentiation toward pathogenic Th1 and Th17 cells.
Published May 23, 2018
Scientific Show Stopper
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REV-ERBα controls the clock in the lung
In this episode, David Ray, Marie Pariollaud and colleagues identify REV-ERBα as a critical regulator of rhythmic inflammatory responses in the lung…
Published April 30, 2018
Author's Take
Immune tolerance-like pathway inhibits repair following white matter injury
Stephen Back and colleagues identify an immune tolerance-like pathway that prevents repair after white matter injury…
Published April 16, 2018
Author's Take
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