Posts

451 items found.
Angiopoietin/Tie2 maintain the flow of Schlemm’s canal
Gou Young Koh, Jaeryung Kim, and Dae-Young Park discuss their work, which identifies angiopoietin/Tie2 as a critical pathway in maintaining the integrity and function of Schlemm’s canal…
Published September 18, 2017
Author's Take
An essential role for YAP/TAZ in developmental and pathogenic angiogenesis
A study from Gou Young Koh's lab at the Korea Advanced Institute of Science and Technology reveals that YAP/TAZ coordinates angiogenesis and vascular remodeling in the brain and retina...
Published August 14, 2017
Scientific Show Stopper
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Non-classical monocytes contribute to treatment resistance against anti-VEGF cancer therapies
Jung et al. describe how immunosuppressive effects of non-classical Ly6C-low monocytes contribute to resistance against anti-VEGF therapies in mouse models of colorectal cancer.
Published July 10, 2017
Scientific Show Stopper
Gene expression profile predicts response to pembrolizumab
In this episode, Terri McClanahan and Jared Lunceford identify a gene expression profile that correlates with a beneficial response to anti-PD-1 therapy
Published June 26, 2017
Author's Take
Ubiquitin ligase RNF146 influences osteoblast proliferation by regulating β-catenin signaling
A study by Matsumoto et al. links regulation of Wnt/β-catenin signaling by the ubiquitin ligase RNF146 as a fate-determining pathway in osteoblastogenesis...
Published June 5, 2017
Scientific Show Stopper
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