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Corrigendum Free access | 10.1172/JCI29069C1

Inflammation and insulin resistance

Steven E. Shoelson, Jongsoon Lee, and Allison B. Goldfine

Find articles by Shoelson, S. in: JCI | PubMed | Google Scholar

Find articles by Lee, J. in: JCI | PubMed | Google Scholar

Find articles by Goldfine, A. in: JCI | PubMed | Google Scholar

Published August 1, 2006 - More info

Published in Volume 116, Issue 8 on August 1, 2006
J Clin Invest. 2006;116(8):2308–2308. https://doi.org/10.1172/JCI29069C1.
© 2006 The American Society for Clinical Investigation
Published August 1, 2006 - Version history
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Inflammation and insulin resistance
Steven E. Shoelson, … , Jongsoon Lee, Allison B. Goldfine
Steven E. Shoelson, … , Jongsoon Lee, Allison B. Goldfine
Review Series

Inflammation and insulin resistance

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Abstract

Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic patients. This should have been an important clue to link inflammation to the pathogenesis of type 2 diabetes (T2D), but the antihyperglycemic and antiinflammatory effects of salicylates were not connected to the pathogenesis of insulin resistance until recently. Together with the discovery of an important role for tissue macrophages, these new findings are helping to reshape thinking about how obesity increases the risk for developing T2D and the metabolic syndrome. The evolving concept of insulin resistance and T2D as having immunological components and an improving picture of how inflammation modulates metabolism provide new opportunities for using antiinflammatory strategies to correct the metabolic consequences of excess adiposity.

Authors

Steven E. Shoelson, Jongsoon Lee, Allison B. Goldfine

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Original citation: J. Clin. Invest.116:1793-1801 (2006). doi:10.1172/JCI29069

Citation for this corrigendum: J. Clin. Invest.116:2308 (2006). doi:10.1172/JCI29069C1

In the original article, reference 77 was cited incorrectly. The corrected reference appears below.

Cinti, S., et al. 2005. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J. Lipid Res.46:2347-2355.

The authors regret this error.

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