Review Series

Nucleic acid therapeutics

Series edited by Bruce Sullenger

The series provides an update on progress in the field of nucleic acid-based therapeutics. Individual articles explore a number of strategies that exploit different facets of DNA and RNA biochemistry towards the development of safe and effective therapeutics.

Articles in series

RNA-transfected dendritic cells in cancer immunotherapy
Duane A. Mitchell, Smita K. Nair
Duane A. Mitchell, Smita K. Nair
Published November 1, 2000
Citation Information: J Clin Invest. 2000;106(9):1065-1069. https://doi.org/10.1172/JCI11405.
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RNA-transfected dendritic cells in cancer immunotherapy

Abstract

Authors

Duane A. Mitchell, Smita K. Nair

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Therapeutic applications of transcription factor decoy oligonucleotides
Michael J. Mann, Victor J. Dzau
Michael J. Mann, Victor J. Dzau
Published November 1, 2000
Citation Information: J Clin Invest. 2000;106(9):1071-1075. https://doi.org/10.1172/JCI11459.
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Therapeutic applications of transcription factor decoy oligonucleotides

Abstract

Authors

Michael J. Mann, Victor J. Dzau

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Catalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biological function
Levon M. Khachigian
Levon M. Khachigian
Published November 15, 2000
Citation Information: J Clin Invest. 2000;106(10):1189-1195. https://doi.org/10.1172/JCI11620.
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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics
Nassim Usman, Lawrence M. Blatt
Nassim Usman, Lawrence M. Blatt
Published November 15, 2000
Citation Information: J Clin Invest. 2000;106(10):1197-1202. https://doi.org/10.1172/JCI11631.
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Series Introduction: Emerging clinical applications of nucleic acids
Bruce A. Sullenger
Bruce A. Sullenger
Published October 15, 2000
Citation Information: J Clin Invest. 2000;106(8):921-922. https://doi.org/10.1172/JCI11343.
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Escort aptamers: a delivery service for diagnosis and therapy
Brian J. Hicke, Andrew W. Stephens
Brian J. Hicke, Andrew W. Stephens
Published October 15, 2000
Citation Information: J Clin Invest. 2000;106(8):923-928. https://doi.org/10.1172/JCI11324.
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Escort aptamers: a delivery service for diagnosis and therapy

Abstract

Authors

Brian J. Hicke, Andrew W. Stephens

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Developing aptamers into therapeutics
Rebekah R. White, … , Bruce A. Sullenger, Christopher P. Rusconi
Rebekah R. White, … , Bruce A. Sullenger, Christopher P. Rusconi
Published October 15, 2000
Citation Information: J Clin Invest. 2000;106(8):929-934. https://doi.org/10.1172/JCI11325.
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Developing aptamers into therapeutics

Abstract

Authors

Rebekah R. White, Bruce A. Sullenger, Christopher P. Rusconi

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