Published April 1, 2016 - More info
Mohit Sachdeva, Jeffrey K. Mito, Chang-Lung Lee, Minsi Zhang, Zhizhong Li, Rebecca D. Dodd, David Cason, Lixia Luo, Yan Ma, David Van Mater, Rebecca Gladdy, Dina C. Lev, Diana M. Cardona, David G. Kirsch
Original citation: J Clin Invest. 2014;124(10):4305–4319. doi:10.1172/JCI77116.
Citation for this corrigendum: J Clin Invest. 2016;126(4):1606. doi:10.1172/JCI86573.
In the process of transferring the miR-182-flox and LSL-miR-182 mice to the Jackson Laboratory, the authors realized that the description of how the LSL-miR-182 mice were generated in the manuscript contained an error. Although the miR-182-flox mice were generated by crossing the mice to a flpO deleter strain to delete the Neo cassette, as was stated in the Methods section, the R26-LSL-miR-182 mice were not crossed to a deleter strain. Instead, the R26-LSL-miR-182 mice that were utilized in this work retained the Neo cassette. Two corrected sentences for the Methods section are below.
Chimeric males were mated to WT C57BL/6 females to generate heterozygotes. These mice were subsequently crossed to a flpO deleter strain to excise the frt-Neo-frt cassette to generate miR-182–flox mice.
The R26-LSL-miR-182 mice that were utilized in this work retained the Neo cassette.
The authors regret the error.