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Mitochondrial energy metabolism in heart failure: a question of balance
Janice M. Huss, Daniel P. Kelly
Janice M. Huss, Daniel P. Kelly
Published March 1, 2005
Citation Information: J Clin Invest. 2005;115(3):547-555. https://doi.org/10.1172/JCI24405.
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Review Series

Mitochondrial energy metabolism in heart failure: a question of balance

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Abstract

The mitochondrion serves a critical role as a platform for energy transduction, signaling, and cell death pathways relevant to common diseases of the myocardium such as heart failure. This review focuses on the molecular regulatory events and downstream effector pathways involved in mitochondrial energy metabolic derangements known to occur during the development of heart failure.

Authors

Janice M. Huss, Daniel P. Kelly

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