Modulation of the Acod1/itaconate pathway differentially affects atherosclerosis severity across genetic models and sexes

¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Find articles by Winter, H. in: PubMed | Google Scholar |

¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Find articles by Glaab, E. in: PubMed | Google Scholar

¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

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¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Find articles by Meiser, J. in: PubMed | Google Scholar

¹Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

²Institute of Pharmacology, Heidelberg University, Heidelberg, Germany

³Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg, Luxembourg

⁴Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany

⁵Department of Internal Medicine-I, University Hospital Aachen, Aachen, Germany

⁶Department of Life Science and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg

⁷Department for Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany

⁸Department for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Find articles by Schneider, J. in: PubMed | Google Scholar