Thyroid Hormone Inhibition of the Prolactin Response to Thyrotropin-Releasing Hormone

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Abstract

The influence of serum triiodothyronine (T3) and thyroxine (T4) concentrations on the release of prolactin in man was studied by determining the prolactin response to synthetic thyrotropin-releasing hormone (TRH) in hypothyroid and hyperthyroid patients before and after correction of their serum thyroid hormone abnormalities. The maximum increment in serum prolactin above the basal level (maximum Δ prolactin) was used as the index of response to TRH.

Authors

Peter J. Snyder, Laurence S. Jacobs, Robert D. Utiger, William H. Daughaday