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The Different Effects on the Serum Lipids and Fecal Steroids of High Carbohydrate Diets Given Orally or Intravenously
Lawrence DenBesten, … , William E. Connor, Lewis D. Stegink
Lawrence DenBesten, … , William E. Connor, Lewis D. Stegink
Published June 1, 1973
Citation Information: J Clin Invest. 1973;52(6):1384-1393. https://doi.org/10.1172/JCI107311.
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Research Article

The Different Effects on the Serum Lipids and Fecal Steroids of High Carbohydrate Diets Given Orally or Intravenously

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Abstract

The hypothesis that diets high in carbohydrate produce hyperlipidemia in man was tested in new experiments which provided all calories either by the intravenous route or orally. After a base-line general diet, eight healthy men were fed fat-free diets consisting of 80% of the calories from glucose and 20% from an amino acid hydrolysate. The calories were adequate to maintain body weight. The solutions (1 cal/ml) were infused by constant drip over a 24 h period through either a superior vena cava catheter or a nasogastric tube. Each feeding was for 12 days in sequence but assigned in random order.

Authors

Lawrence DenBesten, Roberto H. Reyna, William E. Connor, Lewis D. Stegink

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