Elexacaftor/tezacaftor/ivacaftor’s effects on cystic fibrosis infections are maintained but not increased after 3.5-years of treatment

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Sarah J. Morgan, Ellis Coulter, Hannah L. Betts, George M. Solomon, John P. Clancy, Steven M. Rowe, David P. Nichols, Pradeep K. Singh

Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression

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Jade Bath, Elisabet Bjånes, Cengiz Goekeri, Jeff Hsiao, Deniz Uzun, Geraldine Nouailles, Victor Nizet, Katharina Ribbeck

F¹⁸-FDG PET imaging as a diagnostic tool for immune checkpoint inhibitor-associated acute kidney injury

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Shruti Gupta, Olivia Green-Lingren, Sudhir Bhimaniya, Aleksandra Krokhmal, Heather Jacene, Marlies Ostermann, Sugama Chicklore, Ben Sprangers, Christophe M. Deroose, Sandra M. Herrmann, Sophia L. Wells, Sarah A. Kaunfer, Jessica L. Ortega, Clara Garcia-Carro, Michael Bold, Kevin L. Chen, Meghan E. Sise, Pedram Heidari, Wai Lun Will Pak, Meghan D. Lee, Pazit Beckerman, Yael Eshet, Raymond K. Hsu, Miguel Hernandez Pampaloni, Arash Rashidi, Norbert Avril, Vicki Donley, Zain Mithani, Russ Kuker, Muhammad O Awiwi, Mindy X. Wang, Sujal I. Shah, Michael D. Weintraub, Heiko Schoder, Raad B. Chowdhury, Harish Seethapathy, Kerry L. Reynolds, Maria Jose Soler, Ala Abudayyeh, Ilya Glezerman, David E. Leaf

Early ascertainment of genetic diagnoses clarifies impact on medium-term survival following neonatal congenital heart surgery

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Benjamin J. Landis, Benjamin M. Helm, Matthew D. Durbin, Lindsey R. Helvaty, Jeremy L. Herrmann, Michael Johansen, Gabrielle C. Geddes, Stephanie M. Ware

Hepatic lipopolysaccharide binding protein partially uncouples inflammation from fibrosis in MAFLD

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Dan Wang, Ania Baghoomian, Zhengyi Zhang, Ya Cui, Emily C. Whang, Xiang Li, Josue Fraga, Rachel Spellman, Tien S. Dong, We Li, Arpana Gupta, Jihane N. Benhammou, Tamer Sallam

Bi-allelic variants in RINT1 present as early-onset pure hereditary spastic paraplegia

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Vicente Quiroz, Laura Planas-Serra, Abigail Sveden, Amy Tam, Hyo M. Kim, Umar Zubair, Dario Resch, Afshin Saffari, Matt C. Danzi, Stephan Züchner, Maya Chopra, Luca Schierbaum, Aurora Pujol, Erik A. Eklund, Darius Ebrahimi-Fakhari

Relationship between maternal serotonin levels and autism-associated genetic variants

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Amandeep Jutla, Lauren C. Shuffrey, Stephen J. Guter, Kally C. O'Reilly, George M. Anderson, James S. Sutcliffe, Edwin H. Cook, Jeremy Veenstra-VanderWeele

A de novo TLR7 gain-of-function mutation causing severe monogenic lupus in an infant

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Jarmila Stremenova Spegarova, Praisoody Sinnappurajar, Dalila Al Julandani, Rokas Navickas, Helen Griffin, Manisha Ahuja, Angela Grainger, Katie Livingstone, Gillian I. Rice, Fraser Sutherland, Corinne Hayes, Simon Parke, Lewis Pang, Marion R. Roderick, Mary Slatter, Yanick Crow, Athimalaipet V. Ramanan, Sophie Hambleton

Tregs protect against combination checkpoint blockade toxicity induced by T_PH and B cell interactions

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Alyssa Duffy, Maryam I. Azeem, Smriti Kanangat, Melinda Yushak, David Lawson, Madhav V. Dhodapkar, Kavita M. Dhodapkar

Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling

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Emma L. Robinson, Charles A. Tharp, Rushita A. Bagchi, Timothy A. McKinsey