Review Series

NF-kappaB in defense and disease

Series edited by Albert S. Baldwin Jr.

NF-kappaB is a primary effector of human disease. The series highlights the evolutionary conservation of the NF-kappaB pathway and its regulation as well as the diverse functions the transcription factor has in human health and disease.

Articles in series

Toll-like receptor–mediated NF-κB activation: a phylogenetically conserved paradigm in innate immunity
Guolong Zhang, Sankar Ghosh
Guolong Zhang, Sankar Ghosh
Published January 1, 2001
Citation Information: J Clin Invest. 2001;107(1):13-19. doi:10.1172/JCI11837.
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Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
Yumi Yamamoto, Richard B. Gaynor
Yumi Yamamoto, Richard B. Gaynor
Published January 15, 2001
Citation Information: J Clin Invest. 2001;107(2):135-142. doi:10.1172/JCI11914.
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Hostile takeovers: viral appropriation of the NF-kB pathway
John Hiscott, Hakju Kwon, Pierre Génin
John Hiscott, Hakju Kwon, Pierre Génin
Published January 15, 2001
Citation Information: J Clin Invest. 2001;107(2):143-151. doi:10.1172/JCI11918.
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Hostile takeovers: viral appropriation of the NF-kB pathway

Abstract

Authors

John Hiscott, Hakju Kwon, Pierre Génin

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Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
Albert S. Baldwin
Albert S. Baldwin
Published February 1, 2001
Citation Information: J Clin Invest. 2001;107(3):241-246. doi:10.1172/JCI11991.
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NF-κB in neuronal plasticity and neurodegenerative disorders
Mark P. Mattson, Simonetta Camandola
Mark P. Mattson, Simonetta Camandola
Published February 1, 2001
Citation Information: J Clin Invest. 2001;107(3):247-254. doi:10.1172/JCI11916.
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NF-κB in neuronal plasticity and neurodegenerative disorders

Abstract

Authors

Mark P. Mattson, Simonetta Camandola

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NF-κB: pivotal mediator or innocent bystander in atherogenesis?
Tucker Collins, Myron I. Cybulsky
Tucker Collins, Myron I. Cybulsky
Published February 1, 2001
Citation Information: J Clin Invest. 2001;107(3):255-264. doi:10.1172/JCI10373.
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NF-κB: pivotal mediator or innocent bystander in atherogenesis?

Abstract

Authors

Tucker Collins, Myron I. Cybulsky

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Series Introduction: The transcription factor NF-κB and human disease
Albert S. Baldwin Jr.
Albert S. Baldwin Jr.
Published January 1, 2001
Citation Information: J Clin Invest. 2001;107(1):3-6. doi:10.1172/JCI11891.
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NF-κB: a key role in inflammatory diseases
Paul P. Tak, Gary S. Firestein
Paul P. Tak, Gary S. Firestein
Published January 1, 2001
Citation Information: J Clin Invest. 2001;107(1):7-11. doi:10.1172/JCI11830.
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NF-κB: a key role in inflammatory diseases

Abstract

Authors

Paul P. Tak, Gary S. Firestein

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