JCI - Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

Published February 1, 2001
Citation Information: J Clin Invest. 2001;107(3):241-246. https://doi.org/10.1172/JCI11991.

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Perspective

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Induction of NF-κB by TNF or other stimuli leads to the transcriptional activation of genes that suppress apoptosis. The proteins encoded by the genes function at different levels in the caspase cascade to block apoptosis.

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

Abstract

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