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The Journal of Clinical Investigation is publishing research that has the potential to change the practice of medicine.

Submissions of interest in the JCI’s Clinical Medicine category include reports of trials that provide an early demonstration of clinically relevant outcomes for new therapies and diagnostics, as well as reports of rigorous observational studies and meta-analyses.

  • Impact Factor: 12.282 (2018). The JCI is one of the top journals in the "Medicine, Research & Experimental" category.
  • Broad readership. The JCI reaches readers across a wide range of medical disciplines and sectors, including members of the American Society for Clinical Investigation (ASCI), an honor association of physician-scientists and the publisher of the JCI. All research is available to all readers for free.
  • Fast decisions. For submissions sent to external reviewers, authors receive decisions under 30 days on average. For submissions that the JCI determines not to be of interest, authors receive decisions within 7 days on average.

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Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

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