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Citation Information: J Clin Invest. 1974;54(2):263-270. https://doi.org/10.1172/JCI107761.
Abstract
Groups of dogs were immunized with sheep erythrocytes administered either directly into the lower respiratory tract (bronchoalveolar spaces) or intravenously. The hemolytic plaque-forming response (Jerne plaque assay) was studied in various canine lymphoid populations (bronchoalveolar cells, hilar lymph nodes, peripheral lymph nodes, and splenic and peripheral blood leukocytes) as a function of time after immunization and as a function of the dose of antigen administered. Serum hemagglutinating antibody titers against sheep erythrocytes were also measured.
Authors
H. B. Kaltreider, L. Kyselka, S. E. Salmon
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