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Gerald L. Mandell, … , Walter Rubin, Edward W. Hook
Citation Information: J Clin Invest. 1970;49(7):1381-1388. https://doi.org/10.1172/JCI106355.
Gerald L. Mandell, … , Walter Rubin, Edward W. Hook
Published July 1, 1970
Citation Information: J Clin Invest. 1970;49(7):1381-1388. https://doi.org/10.1172/JCI106355.
Abstract
Polymorphonuclear neutrophils (PMN) from patients with chronic granulomatous disease of childhood have impaired bactericidal activity and are deficient in diphosphopyridine nucleotide, reduced form of, (NADH) oxidase. Since hydrocortisone had been shown to inhibit NADH oxidation, experiments were undertaken to determine the effect of hydrocortisone on several parameters of human PMN function.
Authors
Gerald L. Mandell, Walter Rubin, Edward W. Hook
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