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Usage Information

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy
Dirk P. Dittmer, Blossom Damania
Dirk P. Dittmer, Blossom Damania
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Review

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

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Abstract

Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. This human gammaherpesvirus was discovered in 1994 by Drs. Yuan Chang and Patrick Moore. Today, there are over five thousand publications on KSHV and its associated malignancies. In this article, we review recent and ongoing developments in the KSHV field, including molecular mechanisms of KSHV pathogenesis, clinical aspects of KSHV-associated diseases, and current treatments for cancers associated with this virus.

Authors

Dirk P. Dittmer, Blossom Damania

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Usage data is cumulative from June 2025 through June 2026.

Usage JCI PMC
Text version 2,329 216
PDF 262 68
Figure 389 0
Citation downloads 152 0
Totals 3,132 284
Total Views 3,416
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ISSN: 0021-9738 (print), 1558-8238 (online)

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