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Usage Information

Molecular targets for tendon neoformation
Hadi Aslan, … , Gadi Pelled, Dan Gazit
Hadi Aslan, … , Gadi Pelled, Dan Gazit
Published February 1, 2008
Citation Information: J Clin Invest. 2008;118(2):439-444. https://doi.org/10.1172/JCI33944.
View: Text | PDF
Review Series

Molecular targets for tendon neoformation

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Abstract

Tendons and ligaments are unique forms of connective tissue that are considered an integral part of the musculoskeletal system. The ultimate function of tendon is to connect muscles to bones and to conduct the forces generated by muscle contraction into movements of the joints, whereas ligaments connect bone to bone and provide joint stabilization. Unfortunately, the almost acellular and collagen I–rich structure of tendons and ligaments makes them very poorly regenerating tissues. Injured tendons and ligaments are considered a major clinical challenge in orthopedic and sports medicine. This Review discusses the several factors that might serve as molecular targets that upon activation can enhance or lead to tendon neoformation.

Authors

Hadi Aslan, Nadav Kimelman-Bleich, Gadi Pelled, Dan Gazit

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Usage data is cumulative from July 2024 through July 2025.

Usage JCI PMC
Text version 652 39
PDF 72 18
Figure 156 3
Citation downloads 87 0
Totals 967 60
Total Views 1,027
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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