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Usage Information

Antimalarial drug resistance
Nicholas J. White
Nicholas J. White
Published April 15, 2004
Citation Information: J Clin Invest. 2004;113(8):1084-1092. https://doi.org/10.1172/JCI21682.
View: Text | PDF
Review Series

Antimalarial drug resistance

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Abstract

Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by the use of antimalarial drug combinations. Artemisinin-derivative combinations are particularly effective, since they act rapidly and are well tolerated and highly effective. Widespread use of these drugs could roll back malaria.

Authors

Nicholas J. White

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Usage data is cumulative from August 2024 through August 2025.

Usage JCI PMC
Text version 4,206 4,959
PDF 334 392
Figure 595 10
Table 79 0
Citation downloads 154 0
Totals 5,368 5,361
Total Views 10,729
(Click and drag on plot area to zoom in. Click legend items above to toggle)

Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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