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Research LetterIn-Press PreviewCardiologyOncology
Open Access | 
10.1172/JCI204909
Single-nuclei transcriptomics reveals cellular senescence in pediatric anthracycline-induced cardiomyopathy
Diwakar Turaga,1 Chang-Ru Tsai,2 Yuka Morikawa,3 Hanna J. Tadros,1 Yi Zhao,3 Lalita Wadhwa,4 Iki Adachi,4 Xiao Li,3 and James F. Martin3
1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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Li, X.
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1Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
2Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
3Texas Heart Institute, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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Martin, J.
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Published August 25, 2026 - More info
Copyright © 2026, Turaga et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Copyright © 2026 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)