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Research LetterIn-Press PreviewImmunologyInfectious disease
Open Access | 
10.1172/JCI171982
IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice
Prashant Rai,1 Martin Sharpe,1 Charan K. Ganta,2 Paul J. Baker,3 Katrin D. Mayer-Barber,3 Brian E. Fee,4 Gregory A. Taylor,4 and Michael B. Fessler1
1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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1Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
2Comparative & Molecular Pathogenesis Branch, National Institute of Environmental Health Sciences, Research Triangle Park, United States of America
3Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, United States of America
4Department of Medicine, Duke University Medical Center, Durham, United States of America
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Published September 12, 2023 - More info
Copyright © 2023, Rai et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Copyright © 2023 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)