Hematoxylin- and eosin-stained tissue sections from Map–SA– or Map+SA–infected mice. (a) Severe osteomyelitis (BALB/c mouse infected with Map+SA). (b) No arthritis or osteomyelitis (BALB/c mouse infected with Map–SA). (c–d) Severe arthritis (nu/nu and nu/+ mice infected with either Map–SA or Map+SA, respectively). (e–f) Kidney sections (BALB/c mice infected with Map–SA or Map+SA, respectively) and (g–h) heart sections (BALB/c mice infected with Map–SA or Map+SA, respectively).