Elevated plus maze test. The percentage of entries into the open arms and the percentage of time spent on the open arms was greater in hybrid (a) and 129SvJae (b) PKCε-null male mice compared with wild-type male littermates. The number of entries into the closed arms was similar in both genotypes regardless of genetic background. Data are mean ± SEM values from 12 hybrid wild-type and 12 hybrid PKCε-null male mice, and 8 wild-type 129SvJae and 7 PKCε-null 129SvJae male mice (two-tailed t tests).