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ViewpointIn-Press Preview Free access | 10.1172/JCI148832
1Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, United States of America
2Department of Medicine and Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, United States of America
3Department of Anesthesiology and Periopertive Medicine, Mayo Clinic, Rochester, United States of America
4Departments of Medicine, Microbiology and Immunology, Albert Einstein College of Medicine, New York, United States of America
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Casadevall, A.
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1Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, United States of America
2Department of Medicine and Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, United States of America
3Department of Anesthesiology and Periopertive Medicine, Mayo Clinic, Rochester, United States of America
4Departments of Medicine, Microbiology and Immunology, Albert Einstein College of Medicine, New York, United States of America
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Henderson, J.
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1Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, United States of America
2Department of Medicine and Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, United States of America
3Department of Anesthesiology and Periopertive Medicine, Mayo Clinic, Rochester, United States of America
4Departments of Medicine, Microbiology and Immunology, Albert Einstein College of Medicine, New York, United States of America
Find articles by Joyner, M. in: JCI | PubMed | Google Scholar
1Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, United States of America
2Department of Medicine and Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, United States of America
3Department of Anesthesiology and Periopertive Medicine, Mayo Clinic, Rochester, United States of America
4Departments of Medicine, Microbiology and Immunology, Albert Einstein College of Medicine, New York, United States of America
Find articles by Pirofski, L. in: JCI | PubMed | Google Scholar
Published February 23, 2021 - More info
In recent months genomic characterization of pandemic SARS-CoV-2 isolates identified viral variants that are less susceptible to neutralization by convalescent plasma (CP), vaccine-elicited plasma/sera, or SARS-CoV-2 monoclonal antibodies than earlier SARS-CoV-2 strains. In this Viewpoint, Casadevall et al. argue against the causal association made in some press articles between the emergence of SARS-CoV-2 variants and convalescent plasma use.