Effect of epimorphin/syntaxin 2 expression on the growth of MIC 216 cell lines. MIC 216 (diamonds), pCEN (squares), EpiS1 (triangles), EpiS2 (times symbols), EpiAS1 (asterisks), and EpiAS2 (circles) were plated at a cell density of 10,000 cells per well in 96-well plates. At various stages of the culture, ten wells for each experimental condition were fixed. Changes in the number of cells were measured using crystal violet staining as described in Methods. Experimental versus control cell lines were compared by one-way ANOVA for independent samples, followed by the Tukey HSD post test. *P < 0.01 for all clones on days 2 and 4, and all clones except EpiS2 versus EpiAS2 on day 8. On day 6, P < 0.01 for all experimental clones versus controls, and for EpiS1 versus EpiAS1.