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Usage Information

CNS-targeting pharmacological interventions for the metabolic syndrome
Kerstin Stemmer, … , Paul T. Pfluger, Matthias H. Tschöp
Kerstin Stemmer, … , Paul T. Pfluger, Matthias H. Tschöp
Published August 5, 2019
Citation Information: J Clin Invest. 2019;129(10):4058-4071. https://doi.org/10.1172/JCI129195.
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Review Series

CNS-targeting pharmacological interventions for the metabolic syndrome

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Abstract

The metabolic syndrome (MetS) encompasses medical conditions such as obesity, hyperglycemia, high blood pressure, and dyslipidemia that are major drivers for the ever-increasing prevalence of type 2 diabetes, cardiovascular diseases, and certain types of cancer. At the core of clinical strategies against the MetS is weight loss, induced by bariatric surgery, lifestyle changes based on calorie reduction and exercise, or pharmacology. This Review summarizes the past, current, and future efforts of targeting the MetS by pharmacological agents. Major emphasis is given to drugs that target the CNS as a key denominator for obesity and its comorbid sequelae.

Authors

Kerstin Stemmer, Timo D. Müller, Richard D. DiMarchi, Paul T. Pfluger, Matthias H. Tschöp

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Usage data is cumulative from July 2024 through July 2025.

Usage JCI PMC
Text version 1,263 273
PDF 231 26
Figure 910 9
Table 167 0
Citation downloads 95 0
Totals 2,666 308
Total Views 2,974
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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