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Research Article Free access | 10.1172/JCI110220

Immunoglobulin G heavy chain (Gm) allotypes in multiple sclerosis.

J P Pandey, J M Goust, J P Salier, and H H Fudenberg

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Published June 1, 1981 - More info

Published in Volume 67, Issue 6 on June 1, 1981
J Clin Invest. 1981;67(6):1797–1800. https://doi.org/10.1172/JCI110220.
© 1981 The American Society for Clinical Investigation
Published June 1, 1981 - Version history
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Abstract

Serum samples from 70 Caucasian patients with multiple sclerosis were typed for nine Gm markers. Significant association was found with the Gm 1,17;21 phenotype, and the relative risk for individuals with this phenotype was calculated at 3.6. The data indicate that Caucasians positive for Gm 1,17;21 are almost four times more likely to develop multiple sclerosis than those without this phenotype.

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