Morphologic observations suggest that the inner layers of the thoracic aorta in man and dog are avascular and the outer layers have vasa vasorum. It appears that vasa vasorum are essential in the thoracic aorta because their interruption produces medial necrosis. These experiments provide the first measurements of blood flow through aortic vasa vasorum and examine physiologic regulation of that flow.


Donald D. Heistad, Melvin L. Marcus, Edward G. Law, Mark L. Armstrong, James C. Ehrhardt, Francois M. Abboud


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