Evidence for Different Gestation-Dependent Effects of Cortisol on Cultured Fetal Lung Cells

• Text
• PDF

Abstract

The effect of cortisol (5.5 μM) on primary monolayer cultures of trypsin-dispersed lung cells from rabbit fetuses of 20-28 days gestation was monitored with respect to (a) cellular growth as determined by DNA content after 72 h, at which time all cultures were in the exponential phase of growth, and (b) cellular maturation as reflected by the incorporation of [14C]-palmitate into saturated lecithin and its release into the culture medium.

Authors

Barry T. Smith, John S. Torday, C. J. P. Giroud