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Usage Information

Nephron Stop-Flow Pressure Response to Obstruction for 24 Hours in the Rat Kidney
William J. Arendshorst, William F. Finn, Carl W. Gottschalk
William J. Arendshorst, William F. Finn, Carl W. Gottschalk
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Nephron Stop-Flow Pressure Response to Obstruction for 24 Hours in the Rat Kidney

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Abstract

Complete ureteral ligation of 24-h duration significantly reduced stop-flow and estimated glomerular capillary pressures in nephrons accessible to micropuncture in obstructed kidneys. In kidneys without ureteral obstruction, a similar response occurred in single tubules blocked for 24 h without affecting nearby unblocked tubules. Thus, the response to tubular obstruction occurs on an individual nephron basis and results from constriction of individual afferent arterioles. The mechanism leading to the response is unknown, but a feedback mechanism operating through the juxtaglomerular apparatus of individual nephrons is an attractive possibility.

Authors

William J. Arendshorst, William F. Finn, Carl W. Gottschalk

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Usage data is cumulative from May 2025 through May 2026.

Usage JCI PMC
Text version 335 12
PDF 152 4
Scanned page 360 6
Citation downloads 248 0
Totals 1,095 22
Total Views 1,117
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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