Thomas E. Riggs, … , A. William Shafer, Clarence A. Guenter
Citation Information: J Clin Invest. 1973;52(10):2660-2663. https://doi.org/10.1172/JCI107459.
Thomas E. Riggs, … , A. William Shafer, Clarence A. Guenter
Published October 1, 1973
Citation Information: J Clin Invest. 1973;52(10):2660-2663. https://doi.org/10.1172/JCI107459.
Abstract
It has been postulated that 2,3-diphosphoglycerate (DPG)-mediated changes in oxyhemoglobin affinity play an important role in oxygen delivery; however, the effect of an acute increase in affinity without changing red cell mass has not been systematically evaluated. This study was designed to measure changes in oxygen transport and oxygen consumption produced by an acute increase in oxyhemoglobin affinity caused by an autologous exchange transfusion using DPG-depleted stored blood.
Authors
Thomas E. Riggs, A. William Shafer, Clarence A. Guenter
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