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Usage Information

Rapid Intravenous Sodium Acetoacetate Infusion in Man METABOLIC AND KINETIC RESPONSES
O. E. Owen, … , M. A. Mozzoli, C. R. Shuman
O. E. Owen, … , M. A. Mozzoli, C. R. Shuman
Published October 1, 1973
Citation Information: J Clin Invest. 1973;52(10):2606-2616. https://doi.org/10.1172/JCI107453.
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Research Article

Rapid Intravenous Sodium Acetoacetate Infusion in Man METABOLIC AND KINETIC RESPONSES

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Abstract

The metabolic and kinetic responses to rapidly intravenously administered sodium acetoacetate (1.0 mmol/kg body wt) was studied after an overnight fast in 12 male and female adults weighing between 88 and 215% of average body weight. Blood was obtained before, during, and after the infusion for determination of circulating concentrations of immunoreactive insulin, glucose, acetoacetate, β-hydroxybutyrate and free fatty acids. In three obese subjects the studies were repeated after 3 and 24 days of total starvation.

Authors

O. E. Owen, G. A. Reichard Jr., H. Markus, G. Boden, M. A. Mozzoli, C. R. Shuman

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Usage data is cumulative from August 2024 through August 2025.

Usage JCI PMC
Text version 226 12
PDF 67 13
Scanned page 509 3
Citation downloads 77 0
Totals 879 28
Total Views 907
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